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General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-110
Gene Name: preproinsulin
Gene Symbol: ins
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: insa (1), zgc:109842

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have hormone activity. Involved in several processes, including negative regulation of feeding behavior; positive regulation of pancreatic A cell differentiation; and type B pancreatic  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns102 Small Deletion Unknown Unknown CRISPR
Targeting reagents:
DISEASE ASSOCIATED WITH ins HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
maturity-onset diabetes of the young type 10 Maturity-onset diabetes of the young, type 10 613370
permanent neonatal diabetes mellitus Diabetes mellitus, permanent neonatal 606176
type 1 diabetes mellitus 2 Diabetes mellitus, insulin-dependent, 2 125852
Hyperproinsulinemia 616214
DISEASE ASSOCIATED WITH ins VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to glucose (more)
Cellular Component extracellular region (more)
Molecular Function hormone activity (more)
GO Terms (all 9)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA ins-201 (1) 485
 Withdrawn Transcriptsextinct
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
SignaFish
ANTIBODIES
PLASMIDSNo data available
MARKER RELATIONSHIPS
insContained in: [BAC] CH211-69I14 (1) (order this), CH211-139A5 (1) (order this)
insEncodes: [cDNA] MGC:109842 (1) (order this), MGC:192614 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_131056 (1) 468bp
Genomic GenBank:AL935065 (1) 167740bp
Select Tool
Polypeptide UniProtKB:B2GSI0 (1) 108aa
Sequence Clusters UniGene:75811 (1)
Sequence Information (all 21)
ORTHOLOGY for ins (Chr: 5)
CITATIONS (294)