ZFIN

ZFIN ID: ZDB-GENE-060503-585

ZFIN ID: ZDB-GENE-060503-585

CITATIONS (116 total)

Gene Name:	solute carrier family 5 member 5
Gene Symbol:	slc5a5

Alt, B., Reibe, S., Feitosa, N.M., Elsalini, O.A., Wendl, T., and Rohr, K.B. (2006) Analysis of origin and growth of the thyroid gland in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(7):1872-1883
Berto-Júnior, C., Santos-Silva, A.P., Ferreira, A.C.F., Graceli, J.B., de Carvalho, D.P., Soares, P., Romeiro, N.C., Miranda-Alves, L. (2018) Unraveling molecular targets of bisphenol A and S in the thyroid gland. Environmental science and pollution research international. 25(27):26916-26926
Chen, Q., Yu, L., Yang, L., and Zhou, B. (2012) Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae. Aquatic toxicology (Amsterdam, Netherlands). 110-111:141-148
Cheng, H., Yan, W., Wu, Q., Liu, C., Gong, X., Hung, T.C., Li, G. (2017) Parental exposure to microcystin-LR induced thyroid endocrine disruption in zebrafish offspring, a transgenerational toxicity. Environmental pollution (Barking, Essex : 1987). 230:981-988
Chu, S., Kwon, B.R., Lee, Y.M., Zoh, K.D., Choi, K. (2021) Effects of 2-ethylhexyl-4-methoxycinnamate (EHMC) on thyroid hormones and genes associated with thyroid, neurotoxic, and nephrotoxic responses in adult and larval zebrafish (Danio rerio). Chemosphere. 263:128176
Concilio, S.C., Zhekova, H.R., Noskov, S.Y., Russell, S.J. (2020) Inter-species variation in monovalent anion substrate selectivity and inhibitor sensitivity in the sodium iodide symporter (NIS). PLoS One. 15:e0229085
de Filippis, T., Marelli, F., Nebbia, G., Porazzi, P., Corbetta, S., Fugazzola, L., Gastaldi, R., Vigone, M.C., Biffanti, R., Frizziero, D., Mandarà, L., Prontera, P., Salerno, M., Maghnie, M., Tiso, N., Radetti, G., Weber, G., Persani, L. (2016) JAG1 loss-of-function variations as a novel predisposing event in the pathogenesis of congenital thyroid defects. The Journal of clinical endocrinology and metabolism. 101(3):861-70
Deng, M., Wu, Y., Xu, C., Jin, Y., He, X., Wan, J., Yu, X., Rao, H., Tu, W. (2017) Multiple approaches to assess the effects of F-53B, a Chinese PFOS alternative, on thyroid endocrine disruption at environmentally relevant concentrations. The Science of the total environment. 624:215-224
Ding, W., Chen, Y., Sultan, Y., Ma, J., Feng, Y., Li, X. (2022) Effect of Acute Exposure to the Ionic Liquid 1-Methyl-3-octylimidazolium Chloride on the Embryonic Development and Larval Thyroid System of Zebrafish. Animals : an open access journal from MDPI. 12(11)
Dong, X., Xu, H., Wu, X., Yang, L. (2017) Multiple bioanalytical method to reveal developmental biological responses in zebrafish embryos exposed to triclocarban. Chemosphere. 193:251-258
Du, J., Wang, S., You, H., Liu, Z. (2016) Effects of ZnO nanoparticles on perfluorooctane sulfonate induced thyroid-disrupting on zebrafish larvae. Journal of environmental sciences (China). 47:153-64
Fang, Y., Wan, J.P., Wang, Z., Song, S.Y., Zhang, C.X., Yang, L., Zhang, Q.Y., Yan, C.Y., Wu, F.Y., Lu, S.Y., Sun, F., Han, B., Zhao, S.X., Dong, M., Song, H.D. (2024) Deficiency of the HGF/Met pathway leads to thyroid dysgenesis by impeding late thyroid expansion. Nature communications. 15:31653165
Fetter, E., Baldauf, L., Da Fonte, D.F., Ortmann, J., Scholz, S. (2015) Comparative analysis of goitrogenic effects of phenylthiourea and methimazole in zebrafish embryos. Reproductive toxicology (Elmsford, N.Y.). 57:10-20
Gao, Y., Liu, Z., Jia, D., Hu, Q., Li, L., Tang, R., Li, D. (2019) Acute microcystin-LR exposure interfere thyroid hormones homeostasis in adult zebrafish (Danio rerio). Chemosphere. 243:125258
Gillotay, P., Shankar, M., Haerlingen, B., Sema Elif, E., Pozo-Morales, M., Garteizgogeascoa, I., Reinhardt, S., Kränkel, A., Bläsche, J., Petzold, A., Ninov, N., Kesavan, G., Lange, C., Brand, M., Lefort, A., Libert, F., Detours, V., Costagliola, S., Singh, S.P. (2020) Single-cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland. EMBO reports. 21(12):e50612
Giusti, N., Gillotay, P., Trubiroha, A., Opitz, R., Dumont, J.E., Costagliola, S., De Deken, X. (2019) Inhibition of the thyroid hormonogenic H₂O₂ production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound. Molecular and Cellular Endocrinology. 500:110635
Guo, Y., Chen, L., Wu, J., Hua, J., Yang, L., Wang, Q., Zhang, W., Lee, J.S., Zhou, B. (2018) Parental co-exposure to bisphenol A and nano-TiO₂ causes thyroid endocrine disruption and developmental neurotoxicity in zebrafish offspring.. The Science of the total environment. 650:557-565
Guzzolino, E., Milella, M.S., Forini, F., Borsò, M., Rutigliano, G., Gorini, F., Zucchi, R., Saba, A., Bianchi, F., Iervasi, G., Pitto, L. (2021) Thyroid disrupting effects of low-dose dibenzothiophene and cadmium in single or concurrent exposure: New evidence from a translational zebrafish model. The Science of the total environment. 769:144703
Han, Z., Li, Y., Zhang, S., Song, N., Xu, H., Dang, Y., Liu, C., Giesy, J.P., Yu, H. (2017) Prenatal transfer of decabromodiphenyl ether (BDE-209) results in disruption of the thyroid system and developmental toxicity in zebrafish offspring. Aquatic toxicology (Amsterdam, Netherlands). 190:46-52
Holloway, N., Riley, B., MacKenzie, D.S. (2020) Expression of the sodium iodide symporter in reproductive and neural tissues of teleost fish. General and comparative endocrinology. 300:113632
Hou, L., Chen, S., Shi, W., Chen, H., Liang, Y., Wang, X., Tan, J., Wang, Y., Deng, X., Zhan, M., Long, J., Cai, G., Luo, S., Zhang, C., Liu, J., Leung, J.Y.S., Xie, L. (2020) Norethindrone alters mating behaviors, ovary histology, hormone production and transcriptional expression of steroidogenic genes in zebrafish (Danio rerio). Ecotoxicology and environmental safety. 195:110496
Hu, F., Zhao, Y., Yuan, Y., Yin, L., Dong, F., Zhang, W., Chen, X. (2021) Effects of environmentally relevant concentrations of tris (2-chloroethyl) phosphate (TCEP) on early life stages of zebrafish (Danio rerio). Environmental Toxicology and Pharmacology. 83:103600
Huang, G.M., Tian, X.F., Fang, X.D., Ji, F.J. (2016) Waterborne exposure to bisphenol F causes thyroid endocrine disruption in zebrafish larvae. Chemosphere. 147:188-194
Huang, Y., Liu, J., Yu, L., Liu, C., Wang, J. (2018) Gonadal impairment and parental transfer of tris (2-butoxyethyl) phosphate in zebrafish after long-term exposure to environmentally relevant concentrations. Chemosphere. 218:449-457
Jia, P.P., Ma, Y.B., Lu, C.J., Mirza, Z., Zhang, W., Jia, Y.F., Li, W.G., Pei, D.S. (2016) The Effects of Disturbance on Hypothalamus-Pituitary-Thyroid (HPT) Axis in Zebrafish Larvae after Exposure to DEHP. PLoS One. 11:e0155762
Jianjie, C., Wenjuan, X., Jinling, C., Jie, S., Ruhui, J., Meiyan, L. (2016) Fluoride caused thyroid endocrine disruption in male zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 171:48-58
Jiao, F., Qiao, K., Jiang, Y., Li, S., Zhao, J., Gui, W. (2019) Integrated thyroid endocrine disrupting effect on zebrafish (Danio rario) larvae via simultaneously repressing type II iodothyronine deiodinase and activating thyroid receptor-mediated signaling following waterborne exposure to trace azocyclotin. Environmental pollution (Barking, Essex : 1987). 255:113328
Junaid, M., Jia, P.P., Tang, Y.M., Xiong, W.X., Huang, H.Y., Strauss, P.R., Li, W.G., Pei, D.S. (2018) Mechanistic toxicity of DEHP at environmentally relevant concentrations (ERCs) and ecological risk assessment in the Three Gorges Reservoir Area, China. Environmental pollution (Barking, Essex : 1987). 242(Pt B):1939-1949
Ka, Y., Lee, I., Ji, K. (2024) Thyroid and growth hormone endocrine disruption and mechanisms of homosalate and octisalate using wild-type, thrαa^-/-, and dre-miR-499^-/- zebrafish embryo/larvae. Ecotoxicology and environmental safety. 286:117170117170
Kim, H., Ji, K. (2019) Exposure to humidifier disinfectants induces developmental effects and disrupts thyroid endocrine systems in zebrafish larvae. Ecotoxicology and environmental safety. 184:109663
Kim, J., Lee, G., Lee, Y.M., Zoh, K.D., Choi, K. (2021) Thyroid disrupting effects of perfluoroundecanoic acid and perfluorotridecanoic acid in zebrafish (Danio rerio) and rat pituitary (GH3) cell line. Chemosphere. 262:128012
Kim, S., Jung, J., Lee, I., Jung, D., Youn, H., Choi, K. (2015) Thyroid disruption by triphenyl phosphate, an organophosphate flame retardant, in zebrafish (Danio rerio) embryos/larvae, and in GH3 and FRTL-5 cell lines. Aquatic toxicology (Amsterdam, Netherlands). 160C:188-196
Kwon, B., Kho, Y., Kim, P.G., Ji, K. (2016) Thyroid endocrine disruption in male zebrafish following exposure to binary mixture of bisphenol AF and sulfamethoxazole. Environmental Toxicology and Pharmacology. 48:168-174
Lee, J., Kim, S., Park, Y.J., Moon, H.B., Choi, K. (2018) Thyroid hormone-disrupting potentials of major benzophenones in two cell lines (GH3 and FRTL-5) and embryo-larval zebrafish. Environmental science & technology. 52(15):8858-8865
Lee, S., Eghan, K., Lee, J., Yoo, D., Yoon, S., Kim, W.K. (2020) Zebrafish Embryonic Exposure to BPAP and Its Relatively Weak Thyroid Hormone-Disrupting Effects. Toxics. 8(4):
Li, P., Li, Z.H., Zhong, L. (2019) Effects of low concentrations of triphenyltin on neurobehavior and the thyroid endocrine system in zebrafish. Ecotoxicology and environmental safety. 186:109776
Liang, X., Li, J., Martyniuk, C.J., Wang, J., Mao, Y., Lu, H., Zha, J. (2017) Benzotriazole ultraviolet stabilizers alter the expression of the thyroid hormone pathway in zebrafish (Danio rerio) embryos. Chemosphere. 182:22-30
Liang, X., Yu, L., Gui, W., Zhu, G. (2015) Exposure to difenoconazole causes changes of thyroid hormone and gene expression levels in zebrafish larvae. Environmental Toxicology and Pharmacology. 40:983-987
Liang, Y.Q., Huang, G.Y., Ying, G.G., Liu, S.S., Jiang, Y.X., Liu, S. (2015) Progesterone and norgestrel alter transcriptional expression of genes along the hypothalamic-pituitary-thyroid axis in zebrafish embryos-larvae. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 167:101-7
Liang, Y.Q., Xu, W., Liang, X., Jing, Z., Pan, C.G., Tian, F. (2020) The synthetic progestin norethindrone causes thyroid endocrine disruption in adult zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 236:108819
Liongue, C., O'Sullivan. L.A., Trengove, M.C., and Ward, A.C. (2012) Evolution of JAK-STAT pathway components: mechanisms and role in immune system development. PLoS One. 7(3):e32777
Liu, C., Yu, H., and Zhang, X. (2013) Zebrafish embryos/larvae for rapid determination of effects on hypothalamic-pituitary-thyroid (HPT) and hypothalamic-pituitary-interrenal (HPI) axis: mRNA expression. Chemosphere. 93(10):2327-32
Liu, C., Zhang, X., Deng, J., Hecker, M., Al-Khedhairy, A., Giesy, J.P., and Zhou, B. (2011) Effects of Prochloraz or Propylthiouracil on the Cross-Talk between the HPG, HPA, and HPT Axes in Zebrafish. Environmental science & technology. 45(2):769-775
Liu, M., Yi, S., Chen, P., Chen, M., Zhong, W., Yang, J., Sun, B., Zhu, L. (2019) Thyroid endocrine disruption effects of perfluoroalkyl phosphinic acids on zebrafish at early development. The Science of the total environment. 676:290-297
Liu, Y., Wang, J., Fang, X., Zhang, H., and Dai, J. (2011) The thyroid-disrupting effects of long-term perfluorononanoate exposure on zebrafish (Danio rerio). Ecotoxicology (London, England). 20(1):47-55
Liu, Y., Wu, D., Xu, Q., Yu, L., Liu, C., Wang, J. (2017) Acute exposure to tris (2-butoxyethyl) phosphate (TBOEP) affects growth and development of embryo-larval zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 191:17-24
Ma, Z., Tang, S., Su, G., Miao, Y., Liu, H., Xie, Y., Giesy, J.P., Saunders, D.M., Hecker, M., Yu, H. (2016) Effects of tris (2-butoxyethyl) phosphate (TBOEP) on endocrine axes during development of early life stages of zebrafish (Danio rerio). Chemosphere. 144:1920-1927
Marelli, F., Carra, S., Agostini, M., Cotelli, F., Peeters, R., Chatterjee, K., Persani, L. (2016) Patterns of thyroid hormone receptor expression in zebrafish and generation of a novel model of resistance to thyroid hormone action. Molecular and Cellular Endocrinology. 424:102-17
Martín, M., Modenutti, C.P., Gil Rosas, M.L., Peyret, V., Geysels, R.C., Bernal Barquero, C.E., Sobrero, G., Muñoz, L., Signorino, M., Testa, G., Miras, M.B., Masini-Repiso, A.M., Calcaterra, N.B., Coux, G., Carrasco, N., Martí, M.A., Nicola, J.P. (2021) A Novel SLC5A5 Variant Reveals the Crucial Role of Kinesin Light Chain 2 in Thyroid Hormonogenesis. The Journal of clinical endocrinology and metabolism. 106(7):1867-1881
Opitz, R., Maquet, E., Zoenen, M., Dadhich, R., and Costagliola, S. (2011) TSH Receptor Function Is Required for Normal Thyroid Differentiation in Zebrafish. Molecular endocrinology (Baltimore, Md.). 25(9):1579-99
Pappalardo, A., Porreca, I., Caputi, L., De Felice, E., Schulte-Merker, S., Zannini, M., Sordino, P. (2015) Thyroid development in zebrafish lacking Taz. Mechanisms of Development. 138 Pt 3:268-78
Porazzi, P., Marelli, F., Benato, F., de Filippis, T., Calebiro, D., Argenton, F., Tiso, N., and Persani, L. (2012) Disruptions of Global and Jagged1-Mediated Notch Signaling Affect Thyroid Morphogenesis in the Zebrafish. Endocrinology. 153(11):5645-5658
Qiao, K., Hu, T., Jiang, Y., Huang, J., Hu, J., Gui, W., Ye, Q., Li, S., Zhu, G. (2020) Crosstalk of cholinergic pathway on thyroid disrupting effects of the insecticide chlorpyrifos in zebrafish (Danio rerio). The Science of the total environment. 757:143769
Ren, X., Wang, W., Zhao, X., Ren, B., Chang, L. (2019) Parental exposure to tris(1,3-dichloro-2-propyl) phosphate results in thyroid endocrine disruption and inhibition of growth in zebrafish offspring. Aquatic toxicology (Amsterdam, Netherlands). 209:132-141
Rurale, G., Marelli, F., Duminuco, P., Persani, L. (2019) Glis3 as a critical regulator of thyroid primordium specification. Thyroid : official journal of the American Thyroid Association. 30(2):277-289
Shi, G., Wang, J., Guo, H., Sheng, N., Cui, Q., Pan, Y., Guo, Y., Sun, Y., Dai, J. (2019) Parental exposure to 6:2 chlorinated polyfluorinated ether sulfonate (F-53B) induced transgenerational thyroid hormone disruption in zebrafish. The Science of the total environment. 665:855-863
Shi, W.J., Ying, G.G., Huang, G.Y., Liang, Y.Q., Hu, L.X., Zhao, J.L., Zhang, J.N. (2017) Transcriptional and Biochemical Alterations in Zebrafish Eleuthero-Embryos (Danio rerio) After Exposure to Synthetic Progestogen Dydrogesterone. Bulletin of environmental contamination and toxicology. 99(1):39-45
Shi, X., Liu, C., Wu, G., and Zhou, B. (2009) Waterborne exposure to PFOS causes disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae. Chemosphere. 77(7):1010-1018
Song, J., Lu, Y., Cheng, X., Shi, C., Lou, Q., Jin, X., He, J., Zhai, G., Yin, Z. (2021) Functions of the Thyroid-Stimulating Hormone on Key Developmental Features Revealed in a Series of Zebrafish Dyshormonogenesis Models. Cells. 10(8):
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Sun, Y., Li, Y., Liu, Z., Chen, Q. (2018) Environmentally relevant concentrations of mercury exposure alter thyroid hormone levels and gene expression in the hypothalamic-pituitary-thyroid axis of zebrafish larvae. Fish physiology and biochemistry. 44(4):1175-1183
Tang, T., Yang, Y., Chen, Y., Tang, W., Wang, F., Diao, X. (2015) Thyroid Disruption in Zebrafish Larvae by Short-Term Exposure to Bisphenol AF. International Journal of Environmental Research and Public Health. 12:13069-13084
Teng, M., Zhu, W., Wang, D., Yan, J., Qi, S., Song, M., Wang, C. (2018) Acute exposure of zebrafish embryo (Danio rerio) to flutolanil reveals its developmental mechanism of toxicity via disrupting the thyroid system and metabolism. Environmental pollution (Barking, Essex : 1987). 242:1157-1165
Thienpont, B., Tingaud-Sequeira, A., Prats, E., Barata, C., Babin, P.J., and Raldúa, D. (2011) Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis. Environmental science & technology. 45(7):7525-7532
Trubiroha, A., Gillotay, P., Giusti, N., Gacquer, D., Libert, F., Lefort, A., Haerlingen, B., De Deken, X., Opitz, R., Costagliola, S. (2018) A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function. Scientific Reports. 8:5647
Tu, W., Xu, C., Jin, Y., Lu, B., Lin, C., Wu, Y., Liu, W. (2016) Permethrin is a potential thyroid-disrupting chemical: In vivo and in silico envidence. Aquatic toxicology (Amsterdam, Netherlands). 175:39-46
Usenko, C.Y., Hopkins, D.C., Trumble, S.J., and Bruce, E.D. (2012) Hydroxylated PBDEs induce developmental arrest in zebrafish. Toxicology and applied pharmacology. 262(1):43-51
Vergauwen, L., Cavallin, J.E., Ankley, G.T., Bars, C., Gabriëls, I.J., Michiels, E.D.G., Fitzpatrick, K.R., Periz-Stanacev, J., Randolph, E.C., Robinson, S.L., Saari, T.W., Schroeder, A.L., Stinckens, E., Swintek, J., Van Cruchten, S.J., Verbueken, E., Villeneuve, D.L., Knapen, D. (2018) Gene transcription ontogeny of hypothalamic-pituitary-thyroid axis development in early-life stage fathead minnow and zebrafish. General and comparative endocrinology. 266:87-100
Wang, H., Dong, F., Zhao, Y., Fu, S., Zhao, H., Liu, S., Zhang, W., Hu, F. (2022) Exposure to diclofenac alters thyroid hormone levels and transcription of genes involved in the hypothalamic-pituitary-thyroid axis in zebrafish embryos/larvae. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 257:109335
Wang, J., Shi, G., Yao, J., Sheng, N., Cui, R., Su, Z., Guo, Y., Dai, J. (2019) Perfluoropolyether carboxylic acids (novel alternatives to PFOA) impair zebrafish posterior swim bladder development via thyroid hormone disruption. Environment International. 134:105317
Wang, Q., Liang, K., Liu, J., Yang, L., Guo, Y., Liu, C., and Zhou, B. (2013) Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic-pituitary-thyroid axis. Aquatic toxicology (Amsterdam, Netherlands). 126C:207-213
Wendl, T., Adzic, D., Schoenebeck, J.J., Scholpp, S., Brand, M., Yelon, D., and Rohr, K.B. (2007) Early developmental specification of the thyroid gland depends on han-expressing surrounding tissue and on FGF signals. Development (Cambridge, England). 134(15):2871-2879
Wu, L., Chen, H., Ru, H., Li, Y., Yao, F., Ni, Z., Zhong, L. (2020) Sex-specific effects of triphenyltin chloride (TPT) on thyroid disruption and metabolizing enzymes in adult zebrafish (Danio rerio). Toxicology letters. 331:143-151
Wu, L., Ru, H., Ni, Z., Zhang, X., Xie, H., Yao, F., Zhang, H., Li, Y., Zhong, L. (2019) Comparative thyroid disruption by o,p'-DDT and p,p'-DDE in zebrafish embryos/larvae. Aquatic toxicology (Amsterdam, Netherlands). 216:105280
Xu, C., Li, T., Hu, C., Guo, H., Ye, J., Li, L., Liu, W., Niu, L. (2021) Waterborne uranium causes toxic effect and thyroid disruption in zebrafish larvae. Ecotoxicology and environmental safety. 208:111585
Xu, C., Niu, L., Guo, H., Sun, X., Chen, L., Tu, W., Dai, Q., Ye, J., Liu, W., Liu, J. (2019) Long-term exposure to the non-steroidal anti-inflammatory drug (NSAID) naproxen causes thyroid disruption in zebrafish at environmentally relevant concentrations. The Science of the total environment. 676:387-395
Xu, C., Niu, L., Liu, J., Sun, X., Zhang, C., Ye, J., Liu, W. (2019) Maternal exposure to fipronil results in sulfone metabolite enrichment and transgenerational toxicity in zebrafish offspring: Indication for an overlooked risk in maternal transfer?. Environmental pollution (Barking, Essex : 1987). 246:876-884
Xu, Y., Zhang, S., Bao, Y., Luan, J., Fu, Z., Sun, M., Zhao, X., Feng, X. (2024) Melatonin protects zebrafish pancreatic development and physiological rhythms from sodium propionate-induced disturbances via the hypothalamic-pituitary-thyroid axis. Journal of the science of food and agriculture. 104(12):7454-7463
Yan, C.Y., Wu, F.Y., Sun, F., Fang, Y., Zhang, R.J., Zhang, C.R., Zhang, C.X., Wang, Z., Yang, R.M., Yang, L., Dong, M., Zhang, Q.Y., Ye, X.P., Song, H.D., Zhao, S.X. (2023) The isl2a transcription factor regulates pituitary development in zebrafish. Frontiers in endocrinology. 14:920548920548
Yan, W., Zhou, Y., Yang, J., Li, S., Hu, D., Wang, J., Chen, J., and Li, G. (2012) Waterborne exposure to microcystin-LR alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis in zebrafish larvae. Chemosphere. 87(11):1301-1307
Yang, F., Li, G., Sang, N. (2019) Embryonic exposure to soil samples from a gangue stacking area induces thyroid hormone disruption in zebrafish. Chemosphere. 236:124337
Yang, L., Tu, P.H., Zhang, C.X., Xie, R.R., Dong, M., Jing, Y., Chen, X., Wei, G., Song, H.D. (2023) Influence of two anti-tumor drugs, pazopanib, and axitinib, on the development and thyroid-axis of zebrafish (Danio rerio) embryos/larvae. Frontiers in endocrinology. 14:12046781204678
Yao, F., Li, Y., Ru, H., Wu, L., Xiao, Z., Ni, Z., Chen, D., Zhong, L. (2020) Thyroid disruption and developmental toxicity caused by triphenyltin (TPT) in zebrafish embryos/larvae. Toxicology and applied pharmacology. 394:114957
Yu, K., Li, X., Qiu, Y., Zeng, X., Yu, X., Wang, W., Yi, X., Huang, L. (2020) Low-dose effects on thyroid disruption in zebrafish by long-term exposure to oxytetracycline. Aquatic toxicology (Amsterdam, Netherlands). 227:105608
Yu, L., Chen, M., Liu, Y., Gui, W., and Zhu, G. (2013) Thyroid endocrine disruption in zebrafish larvae following exposure to hexaconazole and tebuconazole. Aquatic toxicology (Amsterdam, Netherlands). 138-139C:35-42
Yu, L., Deng, J., Shi, X., Liu, C., Yu, K., and Zhou, B. (2010) Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis of zebrafish larvae. Aquatic toxicology (Amsterdam, Netherlands). 97(3):226-233
Zeng, X., Sun, H., Huang, Y., Liu, J., Yu, L., Liu, C., Wang, J. (2018) Effects of environmentally relevant concentrations of tris (2-butoxyethyl) phosphate on growth and transcription of genes involved in the GH/IGF and HPT axes in zebrafish (Danio rerio). Chemosphere. 212:376-384
Zhai, W., Huang, Z., Chen, L., Feng, C., Li, B., Li, T. (2014) Thyroid endocrine disruption in zebrafish larvae after exposure to mono-(2-ethylhexyl) phthalate (MEHP). PLoS One. 9:e92465
Zhang, C., Yang, L., Zhang, H., Wu, F., Zhang, Y., Zhang, K., Wu, C., Li, R., Dong, M., Zhao, S., Song, H. (2024) TAF1 is needed for the proliferation and maturation of thyroid follicle cells via Notch signaling. American journal of physiology. Endocrinology and metabolism. 326(6):E832-E841
Zhang, D.H., Zhou, E.X., Yang, Z.L. (2017) Waterborne exposure to BPS causes thyroid endocrine disruption in zebrafish larvae. PLoS One. 12:e0176927
Zhang, H., Chen, Z.F., Qi, Z., Yan, S.C., Wei, W.W., Liu, G., Cai, Z. (2019) ANALYSIS OF TRANSCRIPTIONAL RESPONSE IN ZEBRAFISH ELEUTHEROEMBRYOS EXPOSED TO CLIMBAZOLE: SIGNALING PATHWAYS AND POTENTIAL BIOMARKERS. Environmental toxicology and chemistry. 38(4):794-805
Zhang, M., Zhao, F., Zhang, J., Shi, J., Tao, H., Ge, H., Guo, W., Liu, D., Cai, Z. (2020) Toxicity and accumulation of 6-OH-BDE-47 and newly synthesized 6,6'-diOH-BDE-47 in early life-stages of Zebrafish (Danio rerio). The Science of the total environment. 763:143036
Zhang, S., Guo, X., Lu, S., Sang, N., Li, G., Xie, P., Liu, C., Zhang, L., Xing, Y. (2018) Exposure to PFDoA causes disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae. Environmental pollution (Barking, Essex : 1987). 235:974-982
Zhao, X., Wang, S., Li, D., You, H., and Ren, X. (2013) Effects of perchlorate on BDE-47-induced alteration thyroid hormone and gene expression of in the hypothalamus-pituitary-thyroid axis in zebrafish larvae. Environmental Toxicology and Pharmacology. 36(3):1176-1185
Zheng, X., Zhu, Y., Liu, C., Liu, H., Giesy, J.P., Hecker, M., Lam, M.H., and Yu, H. (2012) Accumulation and Biotransformation of BDE-47 by Zebrafish Larvae and Teratogenicity and Expression of Genes along the Hypothalamus-Pituitary-Thyroid Axis. Environmental science & technology. 46(23):12943-12951
Zhou, W., Wang, J., Zhang, J., Peng, C., Li, G., Li, D. (2020) Environmentally relevant concentrations of geosmin affect the development, oxidative stress, apoptosis and endocrine disruption of embryo-larval zebrafish. The Science of the total environment. 735:139373
Zhou, W., Wang, Y., Wang, J., Peng, C., Wang, Z., Qin, H., Li, G., Li, D. (2022) β-Ionone causes endocrine disruption, hyperpigmentation and hypoactivity in zebrafish early life stages. The Science of the total environment. 834:155433

Fang, Y., Wan, J.P., Wang, Z., Song, S.Y., Zhang, C.X., Yang, L., Zhang, Q.Y., Yan, C.Y., Wu, F.Y., Lu, S.Y., Sun, F., Han, B., Zhao, S.X., Dong, M., Song, H.D. (2024) Deficiency of the HGF/Met pathway leads to thyroid dysgenesis by impeding late thyroid expansion. Nature communications. 15:31653165
Ka, Y., Lee, I., Ji, K. (2024) Thyroid and growth hormone endocrine disruption and mechanisms of homosalate and octisalate using wild-type, thrαa^-/-, and dre-miR-499^-/- zebrafish embryo/larvae. Ecotoxicology and environmental safety. 286:117170117170
Xu, Y., Zhang, S., Bao, Y., Luan, J., Fu, Z., Sun, M., Zhao, X., Feng, X. (2024) Melatonin protects zebrafish pancreatic development and physiological rhythms from sodium propionate-induced disturbances via the hypothalamic-pituitary-thyroid axis. Journal of the science of food and agriculture. 104(12):7454-7463
Zhang, C., Yang, L., Zhang, H., Wu, F., Zhang, Y., Zhang, K., Wu, C., Li, R., Dong, M., Zhao, S., Song, H. (2024) TAF1 is needed for the proliferation and maturation of thyroid follicle cells via Notch signaling. American journal of physiology. Endocrinology and metabolism. 326(6):E832-E841
Yan, C.Y., Wu, F.Y., Sun, F., Fang, Y., Zhang, R.J., Zhang, C.R., Zhang, C.X., Wang, Z., Yang, R.M., Yang, L., Dong, M., Zhang, Q.Y., Ye, X.P., Song, H.D., Zhao, S.X. (2023) The isl2a transcription factor regulates pituitary development in zebrafish. Frontiers in endocrinology. 14:920548920548
Yang, L., Tu, P.H., Zhang, C.X., Xie, R.R., Dong, M., Jing, Y., Chen, X., Wei, G., Song, H.D. (2023) Influence of two anti-tumor drugs, pazopanib, and axitinib, on the development and thyroid-axis of zebrafish (Danio rerio) embryos/larvae. Frontiers in endocrinology. 14:12046781204678
Ding, W., Chen, Y., Sultan, Y., Ma, J., Feng, Y., Li, X. (2022) Effect of Acute Exposure to the Ionic Liquid 1-Methyl-3-octylimidazolium Chloride on the Embryonic Development and Larval Thyroid System of Zebrafish. Animals : an open access journal from MDPI. 12(11)
Wang, H., Dong, F., Zhao, Y., Fu, S., Zhao, H., Liu, S., Zhang, W., Hu, F. (2022) Exposure to diclofenac alters thyroid hormone levels and transcription of genes involved in the hypothalamic-pituitary-thyroid axis in zebrafish embryos/larvae. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 257:109335
Zhou, W., Wang, Y., Wang, J., Peng, C., Wang, Z., Qin, H., Li, G., Li, D. (2022) β-Ionone causes endocrine disruption, hyperpigmentation and hypoactivity in zebrafish early life stages. The Science of the total environment. 834:155433
Chu, S., Kwon, B.R., Lee, Y.M., Zoh, K.D., Choi, K. (2021) Effects of 2-ethylhexyl-4-methoxycinnamate (EHMC) on thyroid hormones and genes associated with thyroid, neurotoxic, and nephrotoxic responses in adult and larval zebrafish (Danio rerio). Chemosphere. 263:128176
Guzzolino, E., Milella, M.S., Forini, F., Borsò, M., Rutigliano, G., Gorini, F., Zucchi, R., Saba, A., Bianchi, F., Iervasi, G., Pitto, L. (2021) Thyroid disrupting effects of low-dose dibenzothiophene and cadmium in single or concurrent exposure: New evidence from a translational zebrafish model. The Science of the total environment. 769:144703
Hu, F., Zhao, Y., Yuan, Y., Yin, L., Dong, F., Zhang, W., Chen, X. (2021) Effects of environmentally relevant concentrations of tris (2-chloroethyl) phosphate (TCEP) on early life stages of zebrafish (Danio rerio). Environmental Toxicology and Pharmacology. 83:103600
Kim, J., Lee, G., Lee, Y.M., Zoh, K.D., Choi, K. (2021) Thyroid disrupting effects of perfluoroundecanoic acid and perfluorotridecanoic acid in zebrafish (Danio rerio) and rat pituitary (GH3) cell line. Chemosphere. 262:128012
Martín, M., Modenutti, C.P., Gil Rosas, M.L., Peyret, V., Geysels, R.C., Bernal Barquero, C.E., Sobrero, G., Muñoz, L., Signorino, M., Testa, G., Miras, M.B., Masini-Repiso, A.M., Calcaterra, N.B., Coux, G., Carrasco, N., Martí, M.A., Nicola, J.P. (2021) A Novel SLC5A5 Variant Reveals the Crucial Role of Kinesin Light Chain 2 in Thyroid Hormonogenesis. The Journal of clinical endocrinology and metabolism. 106(7):1867-1881
Song, J., Lu, Y., Cheng, X., Shi, C., Lou, Q., Jin, X., He, J., Zhai, G., Yin, Z. (2021) Functions of the Thyroid-Stimulating Hormone on Key Developmental Features Revealed in a Series of Zebrafish Dyshormonogenesis Models. Cells. 10(8):
Xu, C., Li, T., Hu, C., Guo, H., Ye, J., Li, L., Liu, W., Niu, L. (2021) Waterborne uranium causes toxic effect and thyroid disruption in zebrafish larvae. Ecotoxicology and environmental safety. 208:111585
Concilio, S.C., Zhekova, H.R., Noskov, S.Y., Russell, S.J. (2020) Inter-species variation in monovalent anion substrate selectivity and inhibitor sensitivity in the sodium iodide symporter (NIS). PLoS One. 15:e0229085
Gillotay, P., Shankar, M., Haerlingen, B., Sema Elif, E., Pozo-Morales, M., Garteizgogeascoa, I., Reinhardt, S., Kränkel, A., Bläsche, J., Petzold, A., Ninov, N., Kesavan, G., Lange, C., Brand, M., Lefort, A., Libert, F., Detours, V., Costagliola, S., Singh, S.P. (2020) Single-cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland. EMBO reports. 21(12):e50612
Holloway, N., Riley, B., MacKenzie, D.S. (2020) Expression of the sodium iodide symporter in reproductive and neural tissues of teleost fish. General and comparative endocrinology. 300:113632
Hou, L., Chen, S., Shi, W., Chen, H., Liang, Y., Wang, X., Tan, J., Wang, Y., Deng, X., Zhan, M., Long, J., Cai, G., Luo, S., Zhang, C., Liu, J., Leung, J.Y.S., Xie, L. (2020) Norethindrone alters mating behaviors, ovary histology, hormone production and transcriptional expression of steroidogenic genes in zebrafish (Danio rerio). Ecotoxicology and environmental safety. 195:110496
Lee, S., Eghan, K., Lee, J., Yoo, D., Yoon, S., Kim, W.K. (2020) Zebrafish Embryonic Exposure to BPAP and Its Relatively Weak Thyroid Hormone-Disrupting Effects. Toxics. 8(4):
Liang, Y.Q., Xu, W., Liang, X., Jing, Z., Pan, C.G., Tian, F. (2020) The synthetic progestin norethindrone causes thyroid endocrine disruption in adult zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 236:108819
Qiao, K., Hu, T., Jiang, Y., Huang, J., Hu, J., Gui, W., Ye, Q., Li, S., Zhu, G. (2020) Crosstalk of cholinergic pathway on thyroid disrupting effects of the insecticide chlorpyrifos in zebrafish (Danio rerio). The Science of the total environment. 757:143769
Wu, L., Chen, H., Ru, H., Li, Y., Yao, F., Ni, Z., Zhong, L. (2020) Sex-specific effects of triphenyltin chloride (TPT) on thyroid disruption and metabolizing enzymes in adult zebrafish (Danio rerio). Toxicology letters. 331:143-151
Yao, F., Li, Y., Ru, H., Wu, L., Xiao, Z., Ni, Z., Chen, D., Zhong, L. (2020) Thyroid disruption and developmental toxicity caused by triphenyltin (TPT) in zebrafish embryos/larvae. Toxicology and applied pharmacology. 394:114957
Yu, K., Li, X., Qiu, Y., Zeng, X., Yu, X., Wang, W., Yi, X., Huang, L. (2020) Low-dose effects on thyroid disruption in zebrafish by long-term exposure to oxytetracycline. Aquatic toxicology (Amsterdam, Netherlands). 227:105608
Zhang, M., Zhao, F., Zhang, J., Shi, J., Tao, H., Ge, H., Guo, W., Liu, D., Cai, Z. (2020) Toxicity and accumulation of 6-OH-BDE-47 and newly synthesized 6,6'-diOH-BDE-47 in early life-stages of Zebrafish (Danio rerio). The Science of the total environment. 763:143036
Zhou, W., Wang, J., Zhang, J., Peng, C., Li, G., Li, D. (2020) Environmentally relevant concentrations of geosmin affect the development, oxidative stress, apoptosis and endocrine disruption of embryo-larval zebrafish. The Science of the total environment. 735:139373
Gao, Y., Liu, Z., Jia, D., Hu, Q., Li, L., Tang, R., Li, D. (2019) Acute microcystin-LR exposure interfere thyroid hormones homeostasis in adult zebrafish (Danio rerio). Chemosphere. 243:125258
Giusti, N., Gillotay, P., Trubiroha, A., Opitz, R., Dumont, J.E., Costagliola, S., De Deken, X. (2019) Inhibition of the thyroid hormonogenic H₂O₂ production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound. Molecular and Cellular Endocrinology. 500:110635
Jiao, F., Qiao, K., Jiang, Y., Li, S., Zhao, J., Gui, W. (2019) Integrated thyroid endocrine disrupting effect on zebrafish (Danio rario) larvae via simultaneously repressing type II iodothyronine deiodinase and activating thyroid receptor-mediated signaling following waterborne exposure to trace azocyclotin. Environmental pollution (Barking, Essex : 1987). 255:113328
Kim, H., Ji, K. (2019) Exposure to humidifier disinfectants induces developmental effects and disrupts thyroid endocrine systems in zebrafish larvae. Ecotoxicology and environmental safety. 184:109663
Li, P., Li, Z.H., Zhong, L. (2019) Effects of low concentrations of triphenyltin on neurobehavior and the thyroid endocrine system in zebrafish. Ecotoxicology and environmental safety. 186:109776
Liu, M., Yi, S., Chen, P., Chen, M., Zhong, W., Yang, J., Sun, B., Zhu, L. (2019) Thyroid endocrine disruption effects of perfluoroalkyl phosphinic acids on zebrafish at early development. The Science of the total environment. 676:290-297
Ren, X., Wang, W., Zhao, X., Ren, B., Chang, L. (2019) Parental exposure to tris(1,3-dichloro-2-propyl) phosphate results in thyroid endocrine disruption and inhibition of growth in zebrafish offspring. Aquatic toxicology (Amsterdam, Netherlands). 209:132-141
Rurale, G., Marelli, F., Duminuco, P., Persani, L. (2019) Glis3 as a critical regulator of thyroid primordium specification. Thyroid : official journal of the American Thyroid Association. 30(2):277-289
Shi, G., Wang, J., Guo, H., Sheng, N., Cui, Q., Pan, Y., Guo, Y., Sun, Y., Dai, J. (2019) Parental exposure to 6:2 chlorinated polyfluorinated ether sulfonate (F-53B) induced transgenerational thyroid hormone disruption in zebrafish. The Science of the total environment. 665:855-863
Wang, J., Shi, G., Yao, J., Sheng, N., Cui, R., Su, Z., Guo, Y., Dai, J. (2019) Perfluoropolyether carboxylic acids (novel alternatives to PFOA) impair zebrafish posterior swim bladder development via thyroid hormone disruption. Environment International. 134:105317
Wu, L., Ru, H., Ni, Z., Zhang, X., Xie, H., Yao, F., Zhang, H., Li, Y., Zhong, L. (2019) Comparative thyroid disruption by o,p'-DDT and p,p'-DDE in zebrafish embryos/larvae. Aquatic toxicology (Amsterdam, Netherlands). 216:105280
Xu, C., Niu, L., Guo, H., Sun, X., Chen, L., Tu, W., Dai, Q., Ye, J., Liu, W., Liu, J. (2019) Long-term exposure to the non-steroidal anti-inflammatory drug (NSAID) naproxen causes thyroid disruption in zebrafish at environmentally relevant concentrations. The Science of the total environment. 676:387-395
Xu, C., Niu, L., Liu, J., Sun, X., Zhang, C., Ye, J., Liu, W. (2019) Maternal exposure to fipronil results in sulfone metabolite enrichment and transgenerational toxicity in zebrafish offspring: Indication for an overlooked risk in maternal transfer?. Environmental pollution (Barking, Essex : 1987). 246:876-884
Yang, F., Li, G., Sang, N. (2019) Embryonic exposure to soil samples from a gangue stacking area induces thyroid hormone disruption in zebrafish. Chemosphere. 236:124337
Zhang, H., Chen, Z.F., Qi, Z., Yan, S.C., Wei, W.W., Liu, G., Cai, Z. (2019) ANALYSIS OF TRANSCRIPTIONAL RESPONSE IN ZEBRAFISH ELEUTHEROEMBRYOS EXPOSED TO CLIMBAZOLE: SIGNALING PATHWAYS AND POTENTIAL BIOMARKERS. Environmental toxicology and chemistry. 38(4):794-805
Berto-Júnior, C., Santos-Silva, A.P., Ferreira, A.C.F., Graceli, J.B., de Carvalho, D.P., Soares, P., Romeiro, N.C., Miranda-Alves, L. (2018) Unraveling molecular targets of bisphenol A and S in the thyroid gland. Environmental science and pollution research international. 25(27):26916-26926
Guo, Y., Chen, L., Wu, J., Hua, J., Yang, L., Wang, Q., Zhang, W., Lee, J.S., Zhou, B. (2018) Parental co-exposure to bisphenol A and nano-TiO₂ causes thyroid endocrine disruption and developmental neurotoxicity in zebrafish offspring.. The Science of the total environment. 650:557-565
Huang, Y., Liu, J., Yu, L., Liu, C., Wang, J. (2018) Gonadal impairment and parental transfer of tris (2-butoxyethyl) phosphate in zebrafish after long-term exposure to environmentally relevant concentrations. Chemosphere. 218:449-457
Junaid, M., Jia, P.P., Tang, Y.M., Xiong, W.X., Huang, H.Y., Strauss, P.R., Li, W.G., Pei, D.S. (2018) Mechanistic toxicity of DEHP at environmentally relevant concentrations (ERCs) and ecological risk assessment in the Three Gorges Reservoir Area, China. Environmental pollution (Barking, Essex : 1987). 242(Pt B):1939-1949
Lee, J., Kim, S., Park, Y.J., Moon, H.B., Choi, K. (2018) Thyroid hormone-disrupting potentials of major benzophenones in two cell lines (GH3 and FRTL-5) and embryo-larval zebrafish. Environmental science & technology. 52(15):8858-8865
Sun, Y., Li, Y., Liu, Z., Chen, Q. (2018) Environmentally relevant concentrations of mercury exposure alter thyroid hormone levels and gene expression in the hypothalamic-pituitary-thyroid axis of zebrafish larvae. Fish physiology and biochemistry. 44(4):1175-1183
Teng, M., Zhu, W., Wang, D., Yan, J., Qi, S., Song, M., Wang, C. (2018) Acute exposure of zebrafish embryo (Danio rerio) to flutolanil reveals its developmental mechanism of toxicity via disrupting the thyroid system and metabolism. Environmental pollution (Barking, Essex : 1987). 242:1157-1165
Trubiroha, A., Gillotay, P., Giusti, N., Gacquer, D., Libert, F., Lefort, A., Haerlingen, B., De Deken, X., Opitz, R., Costagliola, S. (2018) A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function. Scientific Reports. 8:5647
Vergauwen, L., Cavallin, J.E., Ankley, G.T., Bars, C., Gabriëls, I.J., Michiels, E.D.G., Fitzpatrick, K.R., Periz-Stanacev, J., Randolph, E.C., Robinson, S.L., Saari, T.W., Schroeder, A.L., Stinckens, E., Swintek, J., Van Cruchten, S.J., Verbueken, E., Villeneuve, D.L., Knapen, D. (2018) Gene transcription ontogeny of hypothalamic-pituitary-thyroid axis development in early-life stage fathead minnow and zebrafish. General and comparative endocrinology. 266:87-100
Zeng, X., Sun, H., Huang, Y., Liu, J., Yu, L., Liu, C., Wang, J. (2018) Effects of environmentally relevant concentrations of tris (2-butoxyethyl) phosphate on growth and transcription of genes involved in the GH/IGF and HPT axes in zebrafish (Danio rerio). Chemosphere. 212:376-384
Zhang, S., Guo, X., Lu, S., Sang, N., Li, G., Xie, P., Liu, C., Zhang, L., Xing, Y. (2018) Exposure to PFDoA causes disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae. Environmental pollution (Barking, Essex : 1987). 235:974-982
Cheng, H., Yan, W., Wu, Q., Liu, C., Gong, X., Hung, T.C., Li, G. (2017) Parental exposure to microcystin-LR induced thyroid endocrine disruption in zebrafish offspring, a transgenerational toxicity. Environmental pollution (Barking, Essex : 1987). 230:981-988
Deng, M., Wu, Y., Xu, C., Jin, Y., He, X., Wan, J., Yu, X., Rao, H., Tu, W. (2017) Multiple approaches to assess the effects of F-53B, a Chinese PFOS alternative, on thyroid endocrine disruption at environmentally relevant concentrations. The Science of the total environment. 624:215-224
Dong, X., Xu, H., Wu, X., Yang, L. (2017) Multiple bioanalytical method to reveal developmental biological responses in zebrafish embryos exposed to triclocarban. Chemosphere. 193:251-258
Han, Z., Li, Y., Zhang, S., Song, N., Xu, H., Dang, Y., Liu, C., Giesy, J.P., Yu, H. (2017) Prenatal transfer of decabromodiphenyl ether (BDE-209) results in disruption of the thyroid system and developmental toxicity in zebrafish offspring. Aquatic toxicology (Amsterdam, Netherlands). 190:46-52
Liang, X., Li, J., Martyniuk, C.J., Wang, J., Mao, Y., Lu, H., Zha, J. (2017) Benzotriazole ultraviolet stabilizers alter the expression of the thyroid hormone pathway in zebrafish (Danio rerio) embryos. Chemosphere. 182:22-30
Liu, Y., Wu, D., Xu, Q., Yu, L., Liu, C., Wang, J. (2017) Acute exposure to tris (2-butoxyethyl) phosphate (TBOEP) affects growth and development of embryo-larval zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 191:17-24
Shi, W.J., Ying, G.G., Huang, G.Y., Liang, Y.Q., Hu, L.X., Zhao, J.L., Zhang, J.N. (2017) Transcriptional and Biochemical Alterations in Zebrafish Eleuthero-Embryos (Danio rerio) After Exposure to Synthetic Progestogen Dydrogesterone. Bulletin of environmental contamination and toxicology. 99(1):39-45
Zhang, D.H., Zhou, E.X., Yang, Z.L. (2017) Waterborne exposure to BPS causes thyroid endocrine disruption in zebrafish larvae. PLoS One. 12:e0176927
de Filippis, T., Marelli, F., Nebbia, G., Porazzi, P., Corbetta, S., Fugazzola, L., Gastaldi, R., Vigone, M.C., Biffanti, R., Frizziero, D., Mandarà, L., Prontera, P., Salerno, M., Maghnie, M., Tiso, N., Radetti, G., Weber, G., Persani, L. (2016) JAG1 loss-of-function variations as a novel predisposing event in the pathogenesis of congenital thyroid defects. The Journal of clinical endocrinology and metabolism. 101(3):861-70
Du, J., Wang, S., You, H., Liu, Z. (2016) Effects of ZnO nanoparticles on perfluorooctane sulfonate induced thyroid-disrupting on zebrafish larvae. Journal of environmental sciences (China). 47:153-64
Huang, G.M., Tian, X.F., Fang, X.D., Ji, F.J. (2016) Waterborne exposure to bisphenol F causes thyroid endocrine disruption in zebrafish larvae. Chemosphere. 147:188-194
Jia, P.P., Ma, Y.B., Lu, C.J., Mirza, Z., Zhang, W., Jia, Y.F., Li, W.G., Pei, D.S. (2016) The Effects of Disturbance on Hypothalamus-Pituitary-Thyroid (HPT) Axis in Zebrafish Larvae after Exposure to DEHP. PLoS One. 11:e0155762
Jianjie, C., Wenjuan, X., Jinling, C., Jie, S., Ruhui, J., Meiyan, L. (2016) Fluoride caused thyroid endocrine disruption in male zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 171:48-58
Kwon, B., Kho, Y., Kim, P.G., Ji, K. (2016) Thyroid endocrine disruption in male zebrafish following exposure to binary mixture of bisphenol AF and sulfamethoxazole. Environmental Toxicology and Pharmacology. 48:168-174
Ma, Z., Tang, S., Su, G., Miao, Y., Liu, H., Xie, Y., Giesy, J.P., Saunders, D.M., Hecker, M., Yu, H. (2016) Effects of tris (2-butoxyethyl) phosphate (TBOEP) on endocrine axes during development of early life stages of zebrafish (Danio rerio). Chemosphere. 144:1920-1927
Marelli, F., Carra, S., Agostini, M., Cotelli, F., Peeters, R., Chatterjee, K., Persani, L. (2016) Patterns of thyroid hormone receptor expression in zebrafish and generation of a novel model of resistance to thyroid hormone action. Molecular and Cellular Endocrinology. 424:102-17
Tu, W., Xu, C., Jin, Y., Lu, B., Lin, C., Wu, Y., Liu, W. (2016) Permethrin is a potential thyroid-disrupting chemical: In vivo and in silico envidence. Aquatic toxicology (Amsterdam, Netherlands). 175:39-46
Fetter, E., Baldauf, L., Da Fonte, D.F., Ortmann, J., Scholz, S. (2015) Comparative analysis of goitrogenic effects of phenylthiourea and methimazole in zebrafish embryos. Reproductive toxicology (Elmsford, N.Y.). 57:10-20
Kim, S., Jung, J., Lee, I., Jung, D., Youn, H., Choi, K. (2015) Thyroid disruption by triphenyl phosphate, an organophosphate flame retardant, in zebrafish (Danio rerio) embryos/larvae, and in GH3 and FRTL-5 cell lines. Aquatic toxicology (Amsterdam, Netherlands). 160C:188-196
Liang, X., Yu, L., Gui, W., Zhu, G. (2015) Exposure to difenoconazole causes changes of thyroid hormone and gene expression levels in zebrafish larvae. Environmental Toxicology and Pharmacology. 40:983-987
Liang, Y.Q., Huang, G.Y., Ying, G.G., Liu, S.S., Jiang, Y.X., Liu, S. (2015) Progesterone and norgestrel alter transcriptional expression of genes along the hypothalamic-pituitary-thyroid axis in zebrafish embryos-larvae. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 167:101-7
Pappalardo, A., Porreca, I., Caputi, L., De Felice, E., Schulte-Merker, S., Zannini, M., Sordino, P. (2015) Thyroid development in zebrafish lacking Taz. Mechanisms of Development. 138 Pt 3:268-78
Tang, T., Yang, Y., Chen, Y., Tang, W., Wang, F., Diao, X. (2015) Thyroid Disruption in Zebrafish Larvae by Short-Term Exposure to Bisphenol AF. International Journal of Environmental Research and Public Health. 12:13069-13084
Zhai, W., Huang, Z., Chen, L., Feng, C., Li, B., Li, T. (2014) Thyroid endocrine disruption in zebrafish larvae after exposure to mono-(2-ethylhexyl) phthalate (MEHP). PLoS One. 9:e92465
Liu, C., Yu, H., and Zhang, X. (2013) Zebrafish embryos/larvae for rapid determination of effects on hypothalamic-pituitary-thyroid (HPT) and hypothalamic-pituitary-interrenal (HPI) axis: mRNA expression. Chemosphere. 93(10):2327-32
Wang, Q., Liang, K., Liu, J., Yang, L., Guo, Y., Liu, C., and Zhou, B. (2013) Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic-pituitary-thyroid axis. Aquatic toxicology (Amsterdam, Netherlands). 126C:207-213
Yu, L., Chen, M., Liu, Y., Gui, W., and Zhu, G. (2013) Thyroid endocrine disruption in zebrafish larvae following exposure to hexaconazole and tebuconazole. Aquatic toxicology (Amsterdam, Netherlands). 138-139C:35-42
Zhao, X., Wang, S., Li, D., You, H., and Ren, X. (2013) Effects of perchlorate on BDE-47-induced alteration thyroid hormone and gene expression of in the hypothalamus-pituitary-thyroid axis in zebrafish larvae. Environmental Toxicology and Pharmacology. 36(3):1176-1185
Chen, Q., Yu, L., Yang, L., and Zhou, B. (2012) Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae. Aquatic toxicology (Amsterdam, Netherlands). 110-111:141-148
Liongue, C., O'Sullivan. L.A., Trengove, M.C., and Ward, A.C. (2012) Evolution of JAK-STAT pathway components: mechanisms and role in immune system development. PLoS One. 7(3):e32777
Porazzi, P., Marelli, F., Benato, F., de Filippis, T., Calebiro, D., Argenton, F., Tiso, N., and Persani, L. (2012) Disruptions of Global and Jagged1-Mediated Notch Signaling Affect Thyroid Morphogenesis in the Zebrafish. Endocrinology. 153(11):5645-5658
Usenko, C.Y., Hopkins, D.C., Trumble, S.J., and Bruce, E.D. (2012) Hydroxylated PBDEs induce developmental arrest in zebrafish. Toxicology and applied pharmacology. 262(1):43-51
Yan, W., Zhou, Y., Yang, J., Li, S., Hu, D., Wang, J., Chen, J., and Li, G. (2012) Waterborne exposure to microcystin-LR alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis in zebrafish larvae. Chemosphere. 87(11):1301-1307
Zheng, X., Zhu, Y., Liu, C., Liu, H., Giesy, J.P., Hecker, M., Lam, M.H., and Yu, H. (2012) Accumulation and Biotransformation of BDE-47 by Zebrafish Larvae and Teratogenicity and Expression of Genes along the Hypothalamus-Pituitary-Thyroid Axis. Environmental science & technology. 46(23):12943-12951
Liu, C., Zhang, X., Deng, J., Hecker, M., Al-Khedhairy, A., Giesy, J.P., and Zhou, B. (2011) Effects of Prochloraz or Propylthiouracil on the Cross-Talk between the HPG, HPA, and HPT Axes in Zebrafish. Environmental science & technology. 45(2):769-775
Liu, Y., Wang, J., Fang, X., Zhang, H., and Dai, J. (2011) The thyroid-disrupting effects of long-term perfluorononanoate exposure on zebrafish (Danio rerio). Ecotoxicology (London, England). 20(1):47-55
Opitz, R., Maquet, E., Zoenen, M., Dadhich, R., and Costagliola, S. (2011) TSH Receptor Function Is Required for Normal Thyroid Differentiation in Zebrafish. Molecular endocrinology (Baltimore, Md.). 25(9):1579-99
Thienpont, B., Tingaud-Sequeira, A., Prats, E., Barata, C., Babin, P.J., and Raldúa, D. (2011) Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis. Environmental science & technology. 45(7):7525-7532
Yu, L., Deng, J., Shi, X., Liu, C., Yu, K., and Zhou, B. (2010) Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis of zebrafish larvae. Aquatic toxicology (Amsterdam, Netherlands). 97(3):226-233
Shi, X., Liu, C., Wu, G., and Zhou, B. (2009) Waterborne exposure to PFOS causes disruption of the hypothalamus-pituitary-thyroid axis in zebrafish larvae. Chemosphere. 77(7):1010-1018
Wendl, T., Adzic, D., Schoenebeck, J.J., Scholpp, S., Brand, M., Yelon, D., and Rohr, K.B. (2007) Early developmental specification of the thyroid gland depends on han-expressing surrounding tissue and on FGF signals. Development (Cambridge, England). 134(15):2871-2879
Alt, B., Reibe, S., Feitosa, N.M., Elsalini, O.A., Wendl, T., and Rohr, K.B. (2006) Analysis of origin and growth of the thyroid gland in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(7):1872-1883
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (19):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2004) Temporary Manual Curation. Manually curated data.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.