Gene
slc5a5
- ID
- ZDB-GENE-060503-585
- Name
- solute carrier family 5 member 5
- Symbol
- slc5a5 Nomenclature History
- Previous Names
-
- NIS (1)
- si:ch211-200a16.4
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in congenital hypothyroidism. Is expressed in thyroid follicle and thyroid primordium. Orthologous to human SLC5A5 (solute carrier family 5 member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 30 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| thyroid dyshormonogenesis 1 | Alliance | Thyroid dyshormonogenesis 1 | 274400 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Sodium/glucose symporter superfamily | Sodium/solute symporter | Sodium:Solute Symporter (SSF) |
|---|---|---|---|---|
|
UniProtKB:A0A8M9Q9Q5
|
438 | |||
|
UniProtKB:A4IG60
|
601 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc5a5-201
(1)
|
Ensembl | 1,698 nt | ||
| mRNA |
slc5a5-202
(1)
|
Ensembl | 2,029 nt |
Interactions and Pathways
No data available
Plasmids
No data available