Publication	Data		Fish	Anatomy
Pálfy et al., 2020	Fig 4		pou5f3zf3267/zf3267	chromatin remodeling disrupted, abnormal
Zhang et al., 2020	Fig. 1		WT + CRISPR1-pou5f3	whole organism dead, abnormal whole organism malformed, abnormal
Liu et al., 2018	Fig. 4		TU + MO1-pou5f3	chromatin organization process quality, abnormal
Dong et al., 2017	Fig. 5		WT + MO1-pou5f3	neuroectoderm hoxb1b expression decreased amount, abnormal
Eckerle et al., 2017	Fig. 3		pou5f3m793/m793	epiboly delayed, abnormal yolk microtubule area density, abnormal yolk microtubule bundle formation process quality, abnormal yolk microtubule cytoskeleton organization process quality, abnormal yolk microtubule polymerization process quality, abnormal yolk syncytial layer microtubule area density, abnormal
	Fig. 4		pou5f3m793/m793	whole organism cyp11a1.1 expression increased amount, abnormal whole organism hsd3b2 expression decreased amount, abnormal whole organism pregnenolone increased amount, abnormal whole organism progesterone decreased amount, abnormal
	Fig. 7		pou5f3m793/m793	epiboly delayed, abnormal yolk microtubule area density, abnormal yolk microtubule bundle formation process quality, abnormal
Veil et al., 2017	Fig. 3		pou5f3m793/m793	endoderm sox17 expression absent, abnormal
	Fig. 4		pou5f3m793/m793	yolk microtubule structure, abnormal
	Fig. 7		pou5f3m793/m793	epiblast bmp2b expression decreased amount, abnormal epiblast vox expression decreased amount, abnormal whole organism ventral region vent expression decreased amount, abnormal whole organism ventral region vox expression decreased amount, abnormal
Voronina et al., 2016	Fig. 1		pou5f3m793/m793	whole organism vent expression decreased amount, abnormal whole organism vox expression decreased amount, abnormal
	Fig. 2		pou5f3m793/m793	whole organism Ab1-vox labeling decreased amount, abnormal
Kotkamp et al., 2014	Fig. 5		pou5f3m793/m793	epiboly arrested, abnormal epiboly delayed, abnormal
	Fig. 6		pou5f3m793/m793	apoptotic process increased process quality, abnormal
	Fig. 7		pou5f3m793/m793	apoptotic process increased process quality, abnormal epiboly delayed, abnormal
Kotkamp et al., 2014	Fig. 1		pou5f3m793/m793 (AB/TL)	EVL physical object quality, abnormal
	Fig. 2		pou5f3m793/+ (AB/TL) ,   pou5f3m793/m793 (AB/TL)	ectoderm ventral region physical object quality, abnormal EVL physical object quality, abnormal presumptive ectoderm ventral region physical object quality, abnormal
	Fig. 7		pou5f3m793/m793 (AB/TL)	EVL poorly differentiated, abnormal
Leichsenring et al., 2013	Fig. 2		pou5f3m793/m793	whole organism embryo development arrested, abnormal
	Fig. S8		pou5f3m793/m793	whole organism embryo development arrested, abnormal
Song et al., 2013	Fig. 1		pou5f3m793/m793	epiboly arrested, abnormal epiboly delayed, abnormal
	Fig. 5		pou5f3m793/m793	DEL epiboly delayed, abnormal DEL increased thickness, abnormal epiboly delayed, abnormal EVL epiboly delayed, abnormal
Barresi et al., 2010	Fig. 3		pou5f3hi349Tg/hi349Tg (AB/TU)	anterior commissure astrocyte mislocalised, abnormal anterior commissure defasciculated, abnormal anterior commissure morphology, abnormal cranial nerve II absent, abnormal cranial nerve II decreased thickness, abnormal cranial nerve II defasciculated, abnormal forebrain commissural neuron axon guidance disrupted, abnormal postoptic commissure astrocyte mislocalised, abnormal postoptic commissure defasciculated, abnormal postoptic commissure morphology, abnormal
	Fig. 4		pou5f3hi349Tg/hi349Tg (AB/TU)	hindbrain axon mislocalised, abnormal hindbrain axon morphology, abnormal radial glial cell cell projection disorganized, abnormal
	Fig. 5		pou5f3hi349Tg/hi349Tg (AB/TU)	spinal cord has fewer parts of type ventricular zone radial glial cell, abnormal
Lachnit et al., 2008	Fig. 1		pou5f3m793/m793 (AB)	blastoderm decreased size, abnormal cell migration involved in gastrulation disrupted, abnormal DEL translucent, abnormal epiboly involved in gastrulation with mouth forming second delayed, abnormal germ ring morphology, abnormal marginal blastomere constricted, abnormal shield decreased size, abnormal shield malformed, abnormal yolk morphology, abnormal yolk syncytial layer increased size, abnormal
	Fig. 2		pou5f3m793/m793 (AB)	epiboly involved in gastrulation with mouth forming second delayed, abnormal
	Fig. 3		pou5f3m793/m793 (AB)	yolk syncytial layer actin filament spatial pattern, abnormal yolk syncytial layer cortical cytoskeleton morphology, abnormal yolk syncytial layer microtubule disorganized, abnormal yolk syncytial layer microtubule spatial pattern, abnormal yolk syncytial layer morphology, abnormal yolk syncytial layer vesicle present, abnormal
	Fig. 4		pou5f3m793/m793 (AB)	cell morphogenesis disrupted, abnormal EVL blastoderm cell circular, abnormal gastrulation disrupted, abnormal
	Fig. 5		pou5f3m793/m793 (AB)	EVL blastoderm cell morphology, abnormal EVL lamellipodium increased amount, abnormal
	Fig. 7		pou5f3m793/m793 (AB)	epiboly involved in gastrulation with mouth forming second disrupted, abnormal
	Fig. 8		pou5f3m793/m793 (AB)	cell-cell adhesion disrupted, abnormal
	Fig. S11		pou5f3hi349Tg/hi349Tg ,   pou5f3m793/m793 (AB)	EVL blastoderm cell morphology, abnormal EVL lamellipodium increased amount, abnormal
	Fig. S2		pou5f3hi349Tg/hi349Tg ,   pou5f3m793/m793 (AB)	epiboly involved in gastrulation with mouth forming second delayed, abnormal
	Fig. S3		pou5f3m793/m793 (AB) ,   pou5f3m793/+ (AB)	cell morphogenesis disrupted, abnormal epiboly involved in gastrulation with mouth forming second delayed, abnormal EVL blastoderm cell circular, abnormal yolk syncytial layer actin filament spatial pattern, abnormal
	Fig. S6		pou5f3m793/+ (AB)	yolk syncytial layer cortical cytoskeleton morphology, abnormal yolk syncytial layer microtubule disorganized, abnormal
	Fig. S7		pou5f3m793/m793 (AB)	yolk syncytial layer morphology, abnormal yolk syncytial layer vesicle present, abnormal
Phenotype Annotation (1994-2006)	Fig. for (e68)		pou5f3e68	midbrain hindbrain boundary quality, abnormal
	Fig. for (e713)		pou5f3e713/e713	hindbrain quality, abnormal midbrain quality, abnormal
	Fig. for (hi1757)		pou5f3hi1757Tg	inner ear quality, abnormal midbrain hindbrain boundary quality, abnormal otolith quality, abnormal whole organism decreased length, abnormal
	Fig. for (hi1940)		pou5f3hi1940Tg	inner ear quality, abnormal midbrain hindbrain boundary quality, abnormal otolith quality, abnormal whole organism decreased length, abnormal
	Fig. for (hi349)		pou5f3hi349Tg	brain quality, abnormal hindbrain quality, abnormal inner ear quality, abnormal midbrain quality, abnormal otolith quality, abnormal sensory system quality, abnormal
	Fig. for (m216)		pou5f3m216/m216 (AB)	midbrain hindbrain boundary quality, abnormal
	Fig. for (m308)		pou5f3m308/m308 (AB)	midbrain hindbrain boundary quality, abnormal
	Fig. for (m793)		pou5f3m793/m793 (AB)	hindbrain quality, abnormal midbrain quality, abnormal
	Fig. for (wi270)		pou5f3wi270Tg	midbrain hindbrain boundary quality, abnormal
Reim et al., 2006	Fig. 1		pou5f3hi349Tg/+ ,   pou5f3hi349Tg/hi349Tg	embryonic morphogenesis disrupted, abnormal gastrulation arrested, abnormal germ ring increased thickness, abnormal notochord decreased length, abnormal notochord malformed, abnormal shield increased thickness, abnormal somite fused with somite, abnormal whole organism wholly dorsalized, abnormal
	Fig. 2		pou5f3hi349Tg/hi349Tg	endoderm development disrupted, abnormal neuroectoderm increased size, abnormal non neural ectoderm decreased size, abnormal pronephric duct morphology, abnormal
	Fig. 3		pou5f3hi349Tg/hi349Tg	dorsal/ventral pattern formation disrupted, abnormal
Amsterdam et al., 2004	text only		pou5f3hi349Tg/hi349Tg	head decreased size, abnormal inner ear lacks all parts of type otolith, abnormal midbrain hindbrain boundary morphology, abnormal trunk decreased length, abnormal
Riley et al., 2004	Fig. 4		pou5f3hi349Tg/hi349Tg	embryonic pattern specification disrupted, abnormal hindbrain commissure neuron decreased amount, abnormal hindbrain development disrupted, abnormal hindbrain disorganized, abnormal hindbrain radial glial cell disorganized, abnormal primary neuron axon fasciculation, abnormal rhombomere primary neuron crowded, abnormal rhombomere primary neuron disorganized, abnormal
Golling et al., 2002	Fig. 1		pou5f3hi349Tg/hi349Tg	hindbrain morphology, abnormal midbrain morphology, abnormal otolith organ has fewer parts of type otolith, abnormal
Brand et al., 1996	text only		pou5f3m308/m308 (AB) ,   pou5f3m216/m216 (AB)	blood circulation disrupted, abnormal cerebellum aplastic, abnormal midbrain hindbrain boundary aplastic, abnormal optic tectum increased size, abnormal otic vesicle morphology, abnormal
Brand et al., 1996	Table 1		pou5f3m216/m216 (AB) ,   pou5f3m308/m308 (AB)	blood circulation disrupted, abnormal cerebellum aplastic, abnormal inner ear decreased size, abnormal midbrain hindbrain boundary aplastic, abnormal post-vent region curved ventral, abnormal
Schier et al., 1996	Fig. 2		pou5f3m216/m216 (AB)	hindbrain morphology, abnormal midbrain hindbrain boundary hypoplastic, abnormal otic vesicle decreased size, abnormal
	Fig. 3		pou5f3m216/m216 (AB)	midbrain hindbrain boundary absent, abnormal midbrain-hindbrain boundary morphogenesis process quality, abnormal
	Fig. T1		pou5f3m308/m308 (AB)	midbrain hindbrain boundary hypoplastic, abnormal