ZFIN ID: ZDB-FIG-101111-17
Barresi et al., 2010 - Essential genes for astroglial development and axon pathfinding during zebrafish embryogenesis. Developmental dynamics : an official publication of the American Association of Anatomists   239(10):2603-2618 Full text @ Dev. Dyn.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibodies:
Fish:
Anatomical Terms:
Stage: Prim-25
PHENOTYPE:
Fish:
Observed In:
Stage: Prim-25

Fig. 3 Forebrain mutants. A-X: Ventral views of zebrafish forebrains showing axons (αAT, green) and astroglial cells (αGfap, red). Anterior is up. A: WT forebrain commissures. Insets show POC (left) and the corresponding glial bridge (right) as single channels. Commissures and the optic chiasm all cross at the midline as cohesive bundles in direct association with glial bridges. B-X: Mutants with defects in forebrain astroglia and/or axonal anatomy. B: rrm2 mutants, known to have widespread necrosis, display severe astroglial reductions and dramatic optic nerve and commissural axon phenotypes including reductions and pathfinding errors. Mutants that had reduced or absent optic nerves include: (C) wnt5b, (D) gnl3, (E) bysl, (K) twistnb, (L,M) ppp1r12a, (N) utp11l, (O) mak16, (P) pou5f1,(Q) pes, (R) lamb1, (S) hnf1b, (T) abhd11, (U,V) esco2, and (W) kif11. Optic nerves were defasciculated in: (G) cdh2, (H) mpp5a, and (I) copa mutants. RGC axons made pathfinding errors in; (J) sfpq, (L) ppp1r12a, and (C) wnt5b mutants. Mutants having defasciculated commissures and/or axon pathfinding errors were; (C) wnt5b, (G) cdh2, (H) mpp5a, (L,M) ppp1r12a,(O) mak16, (P) pou5f1, (Q) pes, (R) lamb1, (S) hnf1b, (T) abhd11, (W) kif11, and (X) csnk1a1. The only mutants that did not exhibit astroglial patterning defects were (E) bysl, (G) cdh2, and (S) hnf1b. Insets show enlargements of boxed regions in the corresponding images. Arrows indicate mislocated axons phenotypes in the AC, POC (C,F,K-O), or optic nerves (S). Arrowheads highlight locations of specific axonal pathfinding errors (C,H-J,Q-T,W), astroglial defects (X), or the beginning of the optic nerves (F). White dots denote location of ectopic astoglial cell bodies at the forebrain ventricular zone (W, inset).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
gfap Ab4-gfap WT standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap abhd11hi3305Tg/hi3305Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap byslhi3351Tg/hi3351Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap cdh2hi3644Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap copahi1872Tg/hi1872Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap csnk1a1hi2069Tg/hi2069Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap esco2hi2865Tg/hi2865Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap hnf1bahi1843Tg/hi1843Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap kif11hi3112aTg/hi3112aTg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap lamb1ahi1297Tg/hi1297Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap mak16hi1055aTg/hi1055aTg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap mib1hi904Tg/hi904Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap pals1ahi2226Tg/hi2226Tg standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap peshi2Tg/hi2Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap pou5f3hi349Tg/hi349Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap ppp1r12ahi2653Tg/hi2653Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap rrm2hi1706Tg/hi1706Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap sfpqhi1779Tg/hi1779Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap smohi229Tg/hi229Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap twistnbhi2573aTg/hi2573aTg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap utp11lhi2937Tg/hi2937Tg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Ab4-gfap wnt5bhi1780bTg/hi1780bTg(AB/TU) standard conditions Prim-25 anterior commissure axon IHC
Ab4-gfap Prim-25 anterior commissure glial cell IHC
Ab4-gfap Prim-25 postoptic commissure axon IHC
Ab4-gfap Prim-25 postoptic commissure glial cell IHC
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-tuba IHC WT standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC abhd11hi3305Tg/hi3305Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC byslhi3351Tg/hi3351Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC cdh2hi3644Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC copahi1872Tg/hi1872Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC csnk1a1hi2069Tg/hi2069Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC esco2hi2865Tg/hi2865Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC hnf1bahi1843Tg/hi1843Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC kif11hi3112aTg/hi3112aTg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC lamb1ahi1297Tg/hi1297Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC mak16hi1055aTg/hi1055aTg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC mib1hi904Tg/hi904Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC pals1ahi2226Tg/hi2226Tg standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC peshi2Tg/hi2Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC pou5f3hi349Tg/hi349Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC ppp1r12ahi2653Tg/hi2653Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC rrm2hi1706Tg/hi1706Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC sfpqhi1779Tg/hi1779Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC smohi229Tg/hi229Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC twistnbhi2573aTg/hi2573aTg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC utp11lhi2937Tg/hi2937Tg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
IHC wnt5bhi1780bTg/hi1780bTg(AB/TU) standard conditions Prim-25 anterior commissure axon
IHC Prim-25 anterior commissure glial cell
IHC Prim-25 postoptic commissure axon
IHC Prim-25 postoptic commissure glial cell
Phenotype Details
Fish Conditions Stage Phenotype
abhd11hi3305Tg/hi3305Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure defasciculated, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II absent, abnormal
Prim-25 cranial nerve II decreased thickness, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
Prim-25 postoptic commissure morphology, abnormal
byslhi3351Tg/hi3351Tg(AB/TU) standard conditions Prim-25 cranial nerve II absent, abnormal
Prim-25 cranial nerve II decreased thickness, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
cdh2hi3644Tg/hi3644Tg(AB/TU) standard conditions Prim-25 anterior commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 anterior commissure defasciculated, abnormal
Prim-25 cranial nerve II commissural neuron axon guidance disrupted, abnormal
Prim-25 cranial nerve II decreased thickness, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
copahi1872Tg/hi1872Tg(AB/TU) standard conditions Prim-25 cranial nerve II defasciculated, abnormal
csnk1a1hi2069Tg/hi2069Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain astrocyte morphology, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure morphology, abnormal
esco2hi2865Tg/hi2865Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure defasciculated, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 cranial nerve II decreased thickness, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
Prim-25 postoptic commissure morphology, abnormal
gnl3hi299Tg/hi299Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 cranial nerve II decreased thickness, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure morphology, abnormal
hnf1bahi1843Tg/hi1843Tg(AB/TU) standard conditions Prim-25 anterior commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 anterior commissure defasciculated, abnormal
Prim-25 cranial nerve II commissural neuron axon guidance disrupted, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 cranial nerve II decreased thickness, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
kif11hi3112aTg/hi3112aTg(AB/TU) standard conditions Prim-25 cranial nerve II absent, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 forebrain ventricle has extra parts of type astrocyte, abnormal
lamb1ahi1297Tg/hi1297Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure has fewer parts of type astrocyte, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 cranial nerve II decreased thickness, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure decreased size, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
Prim-25 postoptic commissure has fewer parts of type astrocyte, abnormal
mak16hi1055aTg/hi1055aTg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 anterior commissure defasciculated, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II absent, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
Prim-25 postoptic commissure morphology, abnormal
mib1hi904Tg/hi904Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 anterior commissure decreased size, abnormal
Prim-25 anterior commissure has fewer parts of type astrocyte, abnormal
Prim-25 cranial nerve II increased thickness, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure decreased size, abnormal
Prim-25 postoptic commissure has fewer parts of type astrocyte, abnormal
pals1ahi2226Tg/hi2226Tg standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure defasciculated, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
Prim-25 postoptic commissure morphology, abnormal
peshi2Tg/hi2Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 cranial nerve II decreased thickness, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure morphology, abnormal
pou5f3hi349Tg/hi349Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure defasciculated, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II absent, abnormal
Prim-25 cranial nerve II decreased thickness, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
Prim-25 postoptic commissure morphology, abnormal
ppp1r12ahi2653Tg/hi2653Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 anterior commissure defasciculated, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II absent, abnormal
Prim-25 cranial nerve II commissural neuron axon guidance disrupted, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
Prim-25 postoptic commissure morphology, abnormal
rrm2hi1706Tg/hi1706Tg(AB/TU) standard conditions Prim-25 cranial nerve II shape, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
sfpqhi1779Tg/hi1779Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure decreased size, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II commissural neuron axon guidance disrupted, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure morphology, abnormal
twistnbhi2573aTg/hi2573aTg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 anterior commissure defasciculated, abnormal
Prim-25 anterior commissure has fewer parts of type astrocyte, abnormal
Prim-25 cranial nerve II absent, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
Prim-25 postoptic commissure has fewer parts of type astrocyte, abnormal
utp11lhi2937Tg/hi2937Tg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 anterior commissure decreased size, abnormal
Prim-25 anterior commissure has fewer parts of type astrocyte, abnormal
Prim-25 cranial nerve II absent, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure has fewer parts of type astrocyte, abnormal
wnt5bhi1780bTg/hi1780bTg(AB/TU) standard conditions Prim-25 anterior commissure astrocyte mislocalised, abnormal
Prim-25 anterior commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 anterior commissure defasciculated, abnormal
Prim-25 anterior commissure morphology, abnormal
Prim-25 cranial nerve II absent, abnormal
Prim-25 cranial nerve II commissural neuron axon guidance disrupted, abnormal
Prim-25 cranial nerve II decreased size, abnormal
Prim-25 cranial nerve II defasciculated, abnormal
Prim-25 forebrain commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure astrocyte mislocalised, abnormal
Prim-25 postoptic commissure commissural neuron axon guidance disrupted, abnormal
Prim-25 postoptic commissure defasciculated, abnormal
Prim-25 postoptic commissure morphology, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental dynamics : an official publication of the American Association of Anatomists for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dev. Dyn.