FIGURE

Figure 1

ID

ZDB-FIG-221020-56

Publication

Xu et al., 2022 - Wnt/β-Catenin Signaling Pathway Is Strongly Implicated in Cadmium-Induced Developmental Neurotoxicity and Neuroinflammation: Clues from Zebrafish Neurobehavior and In Vivo Neuroimaging

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Figure 1

Cd²⁺ exposure inhibited zebrafish Wnt/β-catenin signaling pathway. (A,B) Western blot analysis and quantitation of β-catenin expression levels in 6 dpf zebrafish larvae exposed to different levels of Cd²⁺. (C–E) qRT-PCR analysis of relative expression of genes involved in Wnt/β-catenin signaling pathway. The values are presented as the mean ± SEM. The results of either nonparametric test or ANOVA followed by multiple comparison test are listed in Table S2. “*” indicates significant differences (* p < 0.05, ** p < 0.01, *** p < 0.001).

Expression Data

Genes:	axin2 ccnd1 ctnnb1 gsk3ba lef1 mgme1 myca wnt4 wnt10b
Antibody:	Ab8-ctnnb
Fish:	AB
Condition:	chemical treatment by environment: cadmium dichloride
Anatomical Term:	whole organism
Stage:	Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	chemical treatment by environment: cadmium dichloride
Observed In:	whole organism
Stage:	Day 6

Phenotype Detail

Acknowledgments

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