Gene
wnt10b
- ID
- ZDB-GENE-980526-524
- Name
- wingless-type MMTV integration site family, member 10b
- Symbol
- wnt10b Nomenclature History
- Previous Names
-
- wnt-d (1)
- wnt10br
- wnt[d]
- Zwnt[d]
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have frizzled binding activity. Involved in midbrain-hindbrain boundary development. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in obesity; split hand-foot malformation 6; and tooth agenesis. Is expressed in central nervous system; neural plate; neural rod; and neural tube. Orthologous to human WNT10B (Wnt family member 10B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu346 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| split hand-foot malformation 6 | Alliance | Split-hand/foot malformation 6 | 225300 |
| Tooth agenesis, selective, 8 | 617073 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Wnt | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|
|
UniProtKB:Q801F7
|
427 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
wnt10b-201
(1)
|
Ensembl | 1,515 nt |
Interactions and Pathways
No data available
Plasmids
No data available