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ZIRC
ZFIN ID: ZDB-GENE-980526-362
Gene Name: catenin (cadherin-associated protein), beta 1
Gene Symbol: ctnnb1
Sequence Ontology ID : SO:0000704

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Previous Names: ctnnb (1), id:ibd2058, wu:fb73e10 (1), wu:fi81c06 (1), wu:fk25h01

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits cadherin binding activity. Involved in several processes, including determination of dorsal/ventral asymmetry; glomerular filtration; and positive regulation of Wnt signaling pathway  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hg101 Small Deletion Unknown Unknown CRISPR
la019872Tg Transgenic Insertion Unknown Unknown DNA
sa11589 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH ctnnb1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant non-syndromic intellectual disability 19 Neurodevelopmental disorder with spastic diplegia and visual defects 615075
    colorectal cancer Colorectal cancer, somatic 114500
    exudative vitreoretinopathy 7 Exudative vitreoretinopathy 7 617572
    hepatocellular carcinoma Hepatocellular carcinoma, somatic 114550
    medulloblastoma Medulloblastoma, somatic 155255
    ovarian cancer Ovarian cancer, somatic 167000
    pilomatrixoma Pilomatricoma, somatic 132600
    DISEASE ASSOCIATED WITH ctnnb1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of dorsal/ventral asymmetry (more)
    Cellular Component adherens junction (more)
    Molecular Function cadherin binding (more)
    GO Terms (all 29)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA ctnnb1-002 (1) 881
    mRNA ctnnb1-003 (1) 772
    ctnnb1-201 (1) 3558
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM ctnnb1
    MARKER RELATIONSHIPS
    ctnnb1Contained in: [BAC] CH73-49B13 (1) (order this)
    ctnnb1Contains: [SNP] rs3728768 (1)
    ctnnb1Encodes: [EST] fb73e10 (1), fi81c06 (1), fk25h01, ibd2058 (order this)
    [cDNA] MGC:56048 (1) (order this)
    ctnnb1Has Artifact: [EST] fj58f01
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131059 (1) 3375bp
    Genomic GenBank:AL845513 (1) 164117bp
    Select Tool
    Polypeptide UniProtKB:F1QGH7 (1) 780aa
    Sequence Clusters UniGene:10259 (1)
    Sequence Information (all 24)
    ORTHOLOGY for ctnnb1 (Chr: 16)
    CITATIONS (151)