FIGURE

Figure 2

ID

ZDB-FIG-221020-57

Publication

Xu et al., 2022 - Wnt/β-Catenin Signaling Pathway Is Strongly Implicated in Cadmium-Induced Developmental Neurotoxicity and Neuroinflammation: Clues from Zebrafish Neurobehavior and In Vivo Neuroimaging

Other Figures

All Figure Page

Back to All Figure Page

Figure 2

Activation of Wnt signaling pathway attenuated the adverse effects of Cd²⁺ on zebrafish early development. (A) Schematic design for the following study. (B,C) High-throughput tracking (representative images) of zebrafish early development, and the duration for embryos in different groups to reach certain stages. (D–F) Heart rate, rate of deformed individuals, and body length of 6 dpf zebrafish in different groups. (G) Representative morphological characteristics of zebrafish larvae in each group. The values are presented in boxplots (median and mean, whiskers show 90% confidence levels) or in histograms (mean ± SEM). The results of either nonparametric test or ANOVA followed by multiple comparison test are listed in Table S2. “*” indicates significant differences (* p < 0.05, *** p < 0.001).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: cadmium dichloride chemical treatment by environment: cadmium dichloride chemical treatment by environment: cadmium dichloride chemical treatment by environment: Wnt signalling activator chemical treatment by environment: XAV939
Observed In:	heart contraction pericardium spinal cord whole organism whole organism growth
Stage:	Day 6

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.