FIGURE

Fig. 5

ID

ZDB-FIG-180621-48

Publication

Wang et al., 2018 - Lpar2b Controls Lateral Line Tissue Size by Regulating Yap1 Activity in Zebrafish

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Fig. 5

Lpar2b regulates Yap1 activity. (A,A′) Whole-mount ISH detects the mRNA of yap1 in embryos at 34 hpf. (A′) High-magnification of the pLLP in (A). (B,C) Epifluorescence images of control- or yap1 MO-injected Et(gata2:EGFP)^mp189b embryos at 48 hpf. (D) Quantification of the NM number at 48 hpf and number of pLLP cells at 32 hpf in control- or yap1 MO-injected embryos. (E–F′) Confocal images of the pLLP stained with DAPI (blue) and p-Yap1 (green) at 32 hpf. (G,H) ISH shows a decreased prox1a expression in the pLLP of Lpar2b morphants. The pLLP is outlined by dots. **p < 0.01 compared to control.

Expression Data

Genes:	EGFP prox1a yap1
Antibody:	Ab1-yap1
Fish:	AB AB + MO2-lpar2b zf551Tg zf551Tg + MO2-yap1
Knockdown Reagents:	MO2-lpar2b MO2-yap1
Anatomical Terms:	posterior lateral line neuromast posterior lateral line primordium
Stage Range:	Prim-15 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO2-lpar2b zf551Tg + MO2-yap1
Knockdown Reagents:	MO2-lpar2b MO2-yap1
Observed In:	cell posterior lateral line neuromast posterior lateral line primordium whole organism
Stage Range:	Prim-15 to Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.