FIGURE

Fig. 6

ID

ZDB-FIG-180621-49

Publication

Wang et al., 2018 - Lpar2b Controls Lateral Line Tissue Size by Regulating Yap1 Activity in Zebrafish

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Fig. 6

A phosphorylation-resistant Yap1 mRNA (caYap1) rescued the pLLP and NM phenotype of Lpar2b morphants. (A–C″) Confocal images of the pLLP stained with DAPI (blue) and BrdU (red) at 32 hpf in Et(gata2:EGFP)^mp189b embryos injected with control MO (A–A″), lpar2b MO (B–B″) or lpar2b MO and caYap1 mRNA together (C–C″). The pLLP is outlined by dots. (D–F) Epifluorescence image s of Et(gata2:EGFP)^mp189b embryos injected with control MO (D), lpar2b MO (E), or lpar2b MO and caYap1 mRNA together (F) at 48 hpf. (G–I) Quantification of the total number of cells (G) and the number of BrdU+ cells (H) in the pLLP at 32 hpf, and the number of NMs at 48 hpf (I) in 3 groups of embryos as indicated. *p < 0.05; **p < 0.01.

Expression Data

Gene:	EGFP
Fish:	zf551Tg zf551Tg + MO2-lpar2b
Knockdown Reagent:	MO2-lpar2b
Anatomical Term:	posterior lateral line neuromast
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zf551Tg + MO2-lpar2b
Knockdown Reagent:	MO2-lpar2b
Observed In:	posterior lateral line neuromast whole organism
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.