ZFIN ID: ZDB-FIG-080410-3
Bertrand et al., 2007 - Unexpected Novel Relational Links Uncovered by Extensive Developmental Profiling of Nuclear Receptor Expression. PLoS Genetics   3(11):e188 Full text @ PLoS Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Prim-25 to Long-pec

Fig. 3 Expression of NR genes in the CNS
(A–D) Expression in retina, optic tectum, and hindbrain of RARα-A, Reverbα, Reverbβ, and Reverbγ-B, respectively. RORα-B is expressed in one nucleus in ventral diencephalon and in hindbrain rhombomeres (E), RORα-A in retina, optic tectum, epiphysis, and hypophysis (F), RORβ-A in retina, ventral-posterior part of the optic tectum, and in some neuromasts of the posterior lateral line (G), PXR in small diencephalic and telencephalic nuclei as well as in adenohypophysis (H), PNR in epiphysis, ventral part of retina, and some neurons of posterior diencephalon (I), TLL in diencephalon and mesencephalon with more labeling in ventral diencephalon, anterior tegmentum, and optic tectum (J). COUPTFα-A is expressed in the ventral part of the diencephalon, in forebrain ventricular zone, in tegmentum, and hindbrain (K), COUPTFβ displays a similar expression with additional expression in the dorsal half of the diencephalon (L). EAR2-B expression is restricted to dorsoventral stripes in tegmentum, inentricular zone, in tegmentum, and hindbrain (K), COUPTFβ displays a similar expression with additional expression in the dorsal h hindbrain of rhombencephalon, and in spinal cord (M), COUPTFα-B displays an expression in ventral diencephalon, telencephalon ventricular zone, anterior tegmentum, pretectum, and hindbrain (N). ERβ-A is expressed in a small nucleus in the anterior ventral part of the diencephalon (O), while ERRα is expressed in all brain subdivisions except for the forebrain ventricular zone, tegmentum, and dorsal rhombencephalon (P). ERRβ displays a complex expression with a nucleus in ventral telencephalon, nuclei in diencephalon and tegmentum, and an expression in hindbrain (Q), ERRγ has a very similar expression except for the ventral telencephalic nucleus (R). NURR1 is expressed in part of the telencephalon, in a nucleus in anterior diencephalon, in posterior diencephalon and anterior tegmentum, and in the ventral anterior part of rhombencephalon (S). NOR1 is expressed weakly in ventral telencephalon, tegmentum, and hindbrain and strongly in the habenula (T), SF1-A, LRH1, and SF1-B are expressed strongly in the ventral diencephalon (U–W). RXRα-B is expressed at a low basal level in all brain territories with a much stronger intensity in the ventral part of the optic tectum (X). Embryos are in lateral view, anterior to the left, and are 36 hpf except for (A-D, O, W, and X), where they are at 48 hpf. More extensive anatomical descriptions of these expression patterns are presented in Figure S3 and anatomical details are available at ZFIN (http://zfin.org).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
esr2b WT standard conditions Long-pec diencephalon ISH
esrra WT standard conditions Prim-25 brain ISH
esrrb WT standard conditions Prim-25 diencephalon ISH
Prim-25 hindbrain ISH
Prim-25 tegmentum ISH
Prim-25 telencephalon ISH
esrrga WT standard conditions Prim-25 diencephalon ISH
Prim-25 hindbrain ISH
Prim-25 tegmentum ISH
nr1d1 WT standard conditions Long-pec hindbrain ISH
Long-pec optic tectum ISH
Long-pec retina ISH
nr1d2a WT standard conditions Long-pec hindbrain ISH
Long-pec optic tectum ISH
Long-pec retina ISH
nr1d2b WT standard conditions Long-pec hindbrain ISH
Long-pec optic tectum ISH
Long-pec retina ISH
nr1i2 WT standard conditions Prim-25 adenohypophyseal placode ISH
Prim-25 diencephalon ISH
Prim-25 telencephalon ISH
nr2e1 WT standard conditions Prim-25 diencephalon ISH
Prim-25 optic tectum ISH
Prim-25 tegmentum ISH
nr2e3 WT standard conditions Prim-25 diencephalon ISH
Prim-25 epiphysis ISH
Prim-25 retina ISH
nr2f1a WT standard conditions Prim-25 diencephalon ISH
Prim-25 hindbrain ISH
Prim-25 tegmentum ISH
Prim-25 ventricular zone ISH
nr2f1b WT standard conditions Prim-25 diencephalon ISH
Prim-25 hindbrain ISH
Prim-25 pretectum ISH
Prim-25 tegmentum ISH
Prim-25 ventricular zone ISH
nr2f2 WT standard conditions Prim-25 diencephalon ISH
Prim-25 hindbrain ISH
Prim-25 tegmentum ISH
Prim-25 ventricular zone ISH
nr2f6b WT standard conditions Prim-25 hindbrain ISH
Prim-25 spinal cord ISH
Prim-25 tegmentum ISH
nr4a2b WT standard conditions Prim-25 diencephalon ISH
Prim-25 hindbrain ISH
Prim-25 tegmentum ISH
Prim-25 telencephalon ISH
nr4a3 WT standard conditions Prim-25 epithalamus ISH
Prim-25 hindbrain ISH
Prim-25 tegmentum ISH
Prim-25 telencephalon ISH
nr5a1a WT standard conditions Prim-25 diencephalon ISH
nr5a1b WT standard conditions Long-pec diencephalon ISH
nr5a2 WT standard conditions Prim-25 diencephalon ISH
raraa WT standard conditions Long-pec hindbrain ISH
Long-pec optic tectum ISH
Long-pec retina ISH
roraa WT standard conditions Prim-25 diencephalon ISH
Prim-25 rhombomere ISH
rorab WT standard conditions Prim-25 epiphysis ISH
Prim-25 hypophysis ISH
Prim-25 optic tectum ISH
Prim-25 retina ISH
rorb WT standard conditions Prim-25 optic tectum ISH
Prim-25 posterior lateral line primordium ISH
Prim-25 retina ISH
rxraa WT standard conditions Long-pec brain ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal PLoS Genetics for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS Genet.