ZFIN is now using GRCz12tu for Genomic Data
Gene
nr2f6b
- ID
- ZDB-GENE-040426-2351
- Name
- nuclear receptor subfamily 2, group F, member 6b
- Symbol
- nr2f6b Nomenclature History
- Previous Names
-
- nr2f6
- EAR2-B (1)
- fc72d04
- wu:fc72d04
- zgc:77260
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation; negative regulation of transcription by RNA polymerase II; and nervous system development. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in several structures, including anterior axial hypoblast; axis; gut; mesoderm; and nervous system. Orthologous to human NR2F6 (nuclear receptor subfamily 2 group F member 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 28 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77260 (24 images)
- MGC:77260 (32 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR050274 | Nuclear hormone receptor family NR2 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Nuclear hormone receptor | Nuclear hormone receptor family NR2 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q751 | InterPro | 409 | ||||||
| UniProtKB:Q6P115 | InterPro | 404 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nr2f6b-201
(1)
|
Ensembl | 2,382 nt | ||
| mRNA |
nr2f6b-202
(1)
|
Ensembl | 467 nt | ||
| mRNA |
nr2f6b-203
(1)
|
Ensembl | 603 nt | ||
| mRNA |
nr2f6b-204
(1)
|
Ensembl | 986 nt | ||
| mRNA |
nr2f6b-205
(1)
|
Ensembl | 3,729 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers