Gene

nr1d2b

ID

ZDB-GENE-990415-244

Name

nuclear receptor subfamily 1, group D, member 2b

Symbol

nr1d2b Nomenclature History

Previous Names

NR1D2-B (1)
nr1d2b (1)
Rev-Erb beta 2 (1)
reverbb2
reverbb
zgc:92019 (1)

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding activity; and nuclear receptor transcription coactivator activity. Predicted to be involved in several processes, including hormone-mediated signaling pathway; regulation of circadian rhythm; and regulation of transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription factor complex. Is expressed in nervous system; optic vesicle; and pharyngeal arch. Orthologous to human NR1D2 (nuclear receptor subfamily 1 group D member 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

af342942 (18 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nr1d2b Human Ortholog

No data available

Associated With nr1d2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000536	Nuclear hormone receptor, ligand-binding domain
Domain	IPR001628	Zinc finger, nuclear hormone receptor-type
Family	IPR001723	Nuclear hormone receptor
Homologous_superfamily	IPR013088	Zinc finger, NHR/GATA-type
Homologous_superfamily	IPR035500	Nuclear hormone receptor-like domain superfamily

Domain Details Per Protein

Protein	Length	Nuclear hormone receptor	Nuclear hormone receptor, ligand-binding domain	Nuclear hormone receptor-like domain superfamily	Zinc finger, NHR/GATA-type	Zinc finger, nuclear hormone receptor-type
UniProtKB:A0A8M2B6I7 InterPro	498
UniProtKB:Q6GMI3 InterPro	578

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	nr1d2b-202 (1) Ensembl	Havana	900 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	nr1d2b-203 (1) Ensembl	Havana	3787 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	nr1d2b-003 (1) Ensembl	Havana	613 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	nr1d2b-004 (1) Ensembl	Havana	753 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations