Gene

nr1d2b

ID
ZDB-GENE-990415-244
Name
nuclear receptor subfamily 1, group D, member 2b
Symbol
nr1d2b Nomenclature History
Previous Names
  • NR1D2-B (1)
  • nr1d2b (1)
  • Rev-Erb beta 2 (1)
  • reverbb2
  • reverbb
  • zgc:92019 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding activity; and nuclear receptor transcription coactivator activity. Predicted to be involved in several processes, including hormone-mediated signaling pathway; regulation of circadian rhythm; and regulation of transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription factor complex. Is expressed in nervous system; optic vesicle; and pharyngeal arch. Orthologous to human NR1D2 (nuclear receptor subfamily 1 group D member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nr1d2b Human Ortholog
No data available
Associated With nr1d2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Family IPR050234 Nuclear hormone receptor family NR1 subfamily
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear hormone receptor family NR1 subfamily Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:A0A8M2B6I7 498
UniProtKB:Q6GMI3 578
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript nr1d2b-202 (1) Ensembl 900 nt
mRNA nr1d2b-203 (1) Ensembl 3,787 nt
ncRNA nr1d2b-003 (1) Ensembl 613 nt
ncRNA nr1d2b-004 (1) Ensembl 753 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations