Gene

nr1d1

ID
ZDB-GENE-050105-1
Name
nuclear receptor subfamily 1, group d, member 1
Symbol
nr1d1 Nomenclature History
Previous Names
  • ear1 (1)
  • Reverbalpha (1)
  • zrev-erba (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in autophagy; circadian regulation of gene expression; and regulation of locomotor rhythm. Localizes to chromatin. Is expressed in nervous system. Orthologous to human NR1D1 (nuclear receptor subfamily 1 group D member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
25 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nr1d1 Human Ortholog
No data available
Associated With nr1d1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Family IPR001728 Thyroid hormone receptor
Family IPR050234 Nuclear hormone receptor family NR1 subfamily
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear hormone receptor family NR1 subfamily Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Thyroid hormone receptor Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:F1RAU6 637
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nr1d1-201 (1) Ensembl 2,926 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-nr1d1 polyclonal Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations