Gene

esrra

ID
ZDB-GENE-990415-68
Name
estrogen-related receptor alpha
Symbol
esrra Nomenclature History
Previous Names
  • err1
  • erra (1)
  • esrral
  • ERRalpha (1)
  • NR3B1 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription factor activity. Involved in cell migration involved in gastrulation; regulation of cartilage development; and transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in several structures, including brain; head; mesoderm; muscle; and tail bud. Orthologous to human ESRRA (estrogen related receptor alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With esrra Human Ortholog
No data available
Associated With esrra Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Family IPR024178 Estrogen receptor/oestrogen-related receptor
Family IPR027289 Oestrogen-related receptor
Family IPR050200 Nuclear hormone receptor family NR3 subfamily
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Estrogen receptor/oestrogen-related receptor Nuclear hormone receptor Nuclear hormone receptor family NR3 subfamily Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Oestrogen-related receptor Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:Q6Q6F6 436
UniProtKB:A0A8M2B8J1 441
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA esrra-201 (1) Ensembl 1,274 nt
mRNA esrra-202 (1) Ensembl 347 nt
mRNA esrra-203 (1) Ensembl 1,311 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations