Gene
esrra
- ID
- ZDB-GENE-990415-68
- Name
- estrogen-related receptor alpha
- Symbol
- esrra Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Enables DNA-binding transcription factor activity. Acts upstream of or within DNA-templated transcription; cell migration involved in gastrulation; and regulation of cartilage development. Predicted to be located in chromatin. Predicted to be active in nucleus. Is expressed in several structures, including brain; integument; mesoderm; muscle; and tail bud. Orthologous to human ESRRA (estrogen related receptor alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- ay556395 (26 images)
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR024178 | Estrogen receptor/oestrogen-related receptor |
| Family | IPR027289 | Oestrogen-related receptor |
| Family | IPR050200 | Nuclear hormone receptor family NR3 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Estrogen receptor/oestrogen-related receptor | Nuclear hormone receptor | Nuclear hormone receptor family NR3 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Oestrogen-related receptor | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6Q6F6 | InterPro | 436 | ||||||||
| UniProtKB:A0A8M2B8J1 | InterPro | 441 |
Interactions and Pathways
No data available
Plasmids
No data available