ZFIN ID: ZDB-GENE-030821-2
Gene Name: estrogen-related receptor gamma a
Gene Symbol: esrrga    Nomenclature History

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Previous Names: errg (1), esrrg, ERRgamma (1), NR3B3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Exhibits DNA-binding transcription factor activity. Involved in otic vesicle development and transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in basal plate midbrain region; nervous system; pronephric duct; and tail bud. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Orthologous to several human genes including ESRRG (estrogen related receptor gamma).
Genome Resources: Alliance (1),  Gene:405890 (1),  Ensembl(GRCz11):ENSDARG00000004861 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la020066Tg Transgenic Insertion Unknown Unknown DNA
sa7438 Point Mutation Unknown Missense ENU
sa23108 Point Mutation Unknown Missense, Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32156 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-esrrga N/A 1
    MO2-esrrga N/A 1
    DISEASE ASSOCIATED WITH esrrga HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH esrrga VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA-binding transcription factor activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA esrrga-201 (1)    Ensembl 1991
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM esrrga No data available
    MARKER RELATIONSHIPS
    esrrga Contained in: [BAC] CH211-214O2 (1)
    esrrga Encodes: [EST] ay556397 (2)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212954 (1) 1308 nt
    Genomic GenBank:CT027582 (1) 209608 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F6PD98 (1) 501 aa
    Sequence Information (all 33)
    ORTHOLOGY for esrrga ( Chr: 17 )
    CITATIONS (37)