Gene
esrrga
- ID
- ZDB-GENE-030821-2
- Name
- estrogen-related receptor gamma a
- Symbol
- esrrga Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Exhibits DNA-binding transcription factor activity. Involved in otic vesicle development and transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Is expressed in basal plate midbrain region; nervous system; pronephric duct; and tail bud. Orthologous to several human genes including ESRRG (estrogen related receptor gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- ay556397 (35 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Tohmé et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR024178 | Estrogen receptor/oestrogen-related receptor |
| Family | IPR027289 | Oestrogen-related receptor |
| Family | IPR050200 | Nuclear hormone receptor family NR3 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Estrogen receptor/oestrogen-related receptor | Nuclear hormone receptor | Nuclear hormone receptor family NR3 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Oestrogen-related receptor | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PNM6
|
505 | ||||||||
|
UniProtKB:F6PD98
|
501 | ||||||||
|
UniProtKB:A0A8M9P8U5
|
469 | ||||||||
|
UniProtKB:A0A8M9PNM9
|
446 | ||||||||
|
UniProtKB:A0A8M9PKM0
|
493 | ||||||||
|
UniProtKB:Q6Q6F4
|
435 | ||||||||
|
UniProtKB:A0A8M2B590
|
508 | ||||||||
|
UniProtKB:A0A8M9PE48
|
512 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
esrrga-201
(1)
|
Ensembl | 1,991 nt | ||
| mRNA |
esrrga-202
(1)
|
Ensembl | 1,308 nt |
Interactions and Pathways
No data available
Plasmids