Gene

esrrga

ID
ZDB-GENE-030821-2
Name
estrogen-related receptor gamma a
Symbol
esrrga Nomenclature History
Previous Names
  • errg (1)
  • esrrg
  • ERRgamma (1)
  • NR3B3 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription factor activity. Involved in otic vesicle development and transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in basal plate midbrain region; nervous system; pronephric duct; and tail bud. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Orthologous to several human genes including ESRRG (estrogen related receptor gamma).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tohmé et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With esrrga Human Ortholog
No data available
Associated With esrrga Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Family IPR024178 Oestrogen receptor/oestrogen-related receptor
Family IPR027289 Oestrogen-related receptor
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Oestrogen receptor/oestrogen-related receptor Oestrogen-related receptor Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:Q8QG80 152
UniProtKB:Q6Q6F4 435
UniProtKB:F6PD98 501
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations