ZFIN ID: ZDB-FIG-190314-11
Harjula et al., 2018 - Interleukin 10 mutant zebrafish have an enhanced interferon gamma response and improved survival against a Mycobacterium marinum infection. Scientific Reports   8:10360 Full text @ Sci. Rep.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Terms:
Stage: Adult
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Adult

Unillustrated author statements

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
cd4-1 WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
cd8a WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
foxp3a WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
gata3 WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
ifng1 WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
ighm WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
il1b WT control Adult pleuroperitoneal region RTPCR
WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
il10e46/e46 control Adult pleuroperitoneal region RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
il4 WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
il10 WT standard conditions Adult Not Detected liver RTPCR
Adult pleuroperitoneal region RTPCR
Adult spleen RTPCR
WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
il10e46/e46 standard conditions Adult Not Detected liver RTPCR
Adult pleuroperitoneal region RTPCR
Adult spleen RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
tbx21 WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
tnfa WT control Adult pleuroperitoneal region RTPCR
WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
il10e46/e46 control Adult pleuroperitoneal region RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
tnfb WT control Adult pleuroperitoneal region RTPCR
WT bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
il10e46/e46 control Adult pleuroperitoneal region RTPCR
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney RTPCR
Adult pleuroperitoneal region RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT bacterial treatment by injection: Mycobacterium marinum Adult kidney lymphocyte normal amount, normal
Adult kidney myeloid cell normal amount, normal
il10e46/e46 standard conditions Adult kidney lymphocyte normal amount, normal
Adult kidney myeloid cell normal amount, normal
Adult regulation of chronic inflammatory response process quality, normal
il10e46/e46 bacterial treatment by injection: Mycobacterium marinum Adult kidney cd4-1 expression increased amount, abnormal
Adult kidney gata3 expression decreased amount, abnormal
Adult kidney ifng1 expression increased amount, abnormal
Adult kidney il10 expression increased amount, abnormal
Adult kidney il1b expression decreased amount, abnormal
Adult kidney tnfb expression decreased amount, abnormal
Adult kidney lymphocyte normal amount, normal
Adult kidney myeloid cell increased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Scientific Reports for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Sci. Rep.