ZFIN is now using GRCz12tu for Genomic Data
Gene
cd8a
- ID
- ZDB-GENE-060210-2
- Name
- CD8a molecule
- Symbol
- cd8a Nomenclature History
- Previous Names
-
- zgc:136643
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in T cell mediated immunity; T cell receptor signaling pathway; and cytotoxic T cell differentiation. Predicted to act upstream of or within adaptive immune response. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in immune system; inner ear; and liver. Human ortholog(s) of this gene implicated in immunodeficiency 116. Orthologous to human CD8A (CD8 subunit alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 116 | Alliance | Immunodeficiency 116 | 608957 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CD8 alpha subunit | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain |
|---|---|---|---|---|---|---|
| UniProtKB:Q24JW8 | InterPro | 216 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers