ZFIN is now using GRCz12tu for Genomic Data
Gene
cd8a
- ID
- ZDB-GENE-060210-2
- Name
- CD8a molecule
- Symbol
- cd8a Nomenclature History
- Previous Names
-
- zgc:136643
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to act upstream of or within adaptive immune response. Predicted to be located in plasma membrane. Is expressed in immune system; inner ear; and liver. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human CD8A (CD8 subunit alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 116 | Alliance | Immunodeficiency 116 | 608957 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CD8 alpha subunit | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain |
|---|---|---|---|---|---|---|
| UniProtKB:Q24JW8 | InterPro | 216 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers