ZFIN ID: ZDB-GENE-061116-2
Gene Name: forkhead box P3a
Gene Symbol: foxp3a
Sequence Ontology ID : SO:0000704

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Previous Name: foxp3 (1)

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding activity transcription factor activity and sequence-specific DNA binding activity; involved in regulation of T cell proliferation; predicted to localize to the nucleus;  ...
GENE EXPRESSION
All Expression Data: 7 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu2455]
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026459Tg Transgenic Insertion Unknown Unknown DNA
sa38691 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • um252 Indel Unknown Unknown TALEN
    um253 Small Deletion Unknown Unknown TALEN
    vcc6 Small Deletion Exon 4 Frameshift, Premature Stop TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 3 figures from Sugimoto et al., 2017
    Observed in:
    DISEASE ASSOCIATED WITH foxp3a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked 304790
    type 1 diabetes mellitus {Diabetes mellitus, type I, susceptibility to} 222100
    DISEASE ASSOCIATED WITH foxp3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of T cell proliferation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001766 (1)
  • InterPro:IPR030456 (1)
  • InterPro:IPR032354 (1)
  • InterPro:IPR036388 (1)
  • InterPro:IPR036390 (1)
  • PROSITE:PS00658 (1)
  • PROSITE:PS50039 (1)
  • Pfam:PF00250 (1)
  • Pfam:PF16159 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA foxp3a-201 (1) 1630
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM foxp3a
    MARKER RELATIONSHIPS
    foxp3aContained in: [BAC] CH211-167B20 (1) (order this)
    foxp3aEncodes: [EST] eu2455 (1)
    [cDNA] MGC:171995 (1) (order this), MGC:194759 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001082874 (1) 1630bp
    Genomic GenBank:BX544876 (1) 154624bp
    Select Tool
    Polypeptide UniProtKB:A8WFW7 (1) 419aa
    Sequence Clusters UniGene:116155 (1)
    Sequence Information (all 32)
    OTHER foxp3a GENE PAGES
  • Alliance (1)
  • Gene:571165 (1)
  • VEGA:OTTDARG00000016141 (1)
  • Ensembl(GRCz11):ENSDARG00000055750 (1)
  • ORTHOLOGY for foxp3a (Chr: 8)
    CITATIONS (41)