Gene

foxp3a

ID
ZDB-GENE-061116-2
Name
forkhead box P3a
Symbol
foxp3a Nomenclature History
Previous Names
  • foxp3 (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of T cell proliferation. Predicted to localize to nucleus. Is expressed in digestive system; gill; immune system; and integument. Human ortholog(s) of this gene implicated in Human papillomavirus infectious disease; colorectal cancer; immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; pulmonary tuberculosis; and type 1 diabetes mellitus. Orthologous to human FOXP3 (forkhead box P3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With foxp3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome Alliance Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked 304790
Associated With foxp3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR030456 Fork head domain conserved site 2
Domain IPR001766 Fork head domain
Domain IPR032354 FOXP, coiled-coil domain
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Fork head domain Fork head domain conserved site 2 FOXP, coiled-coil domain Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:A8WFW7 419
UniProtKB:A1L5C8 350
UniProtKB:C3W4Z9 419
UniProtKB:D2EAB6 278
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations