Gene

cd4-1

ID
ZDB-GENE-100922-280
Name
CD4-1 molecule
Symbol
cd4-1 Nomenclature History
Previous Names
  • cd4
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have MHC class II protein binding activity and protein tyrosine kinase binding activity. Predicted to be involved in T cell activation; interleukin-15-mediated signaling pathway; and positive regulation of ERK1 and ERK2 cascade. Localizes to cell surface. Is expressed in blood; digestive system; gill; immune system; and muscle. Orthologous to human CD4 (CD4 molecule).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
19 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cd4-1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 79 Alliance Immunodeficiency 79 619238
OKT4 epitope deficiency 613949
Associated With cd4-1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype
UniProtKB:B5KH12 474
UniProtKB:F1QZB1 474
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cd4-1 polyclonal Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations