Gene
cd4-1
- ID
- ZDB-GENE-100922-280
- Name
- CD4-1 molecule
- Symbol
- cd4-1 Nomenclature History
- Previous Names
-
- cd4
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have MHC class II protein binding activity and protein tyrosine kinase binding activity. Predicted to be involved in T cell activation; interleukin-15-mediated signaling pathway; and positive regulation of ERK1 and ERK2 cascade. Localizes to cell surface. Is expressed in blood; digestive system; gill; immune system; and muscle. Orthologous to human CD4 (CD4 molecule).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 79 | Alliance | Immunodeficiency 79 | 619238 |
| OKT4 epitope deficiency | 613949 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold |
|---|---|---|---|---|---|
|
UniProtKB:B5KH12
|
474 | ||||
|
UniProtKB:F1QZB1
|
474 |
Interactions and Pathways
No data available
Plasmids
No data available