Gene

gata3

ID
ZDB-GENE-990415-82
Name
GATA binding protein 3
Symbol
gata3 Nomenclature History
Previous Names
  • gta3 (1)
  • cb550 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including embryonic organ morphogenesis; generation of neurons; and tissue regeneration. Predicted to localize to nucleus. Used to study hypoparathyroidism-retardation-dysmorphism syndrome. Human ortholog(s) of this gene implicated in hypoparathyroidism; hypoparathyroidism-deafness-renal disease syndrome; nephrosis; and sensorineural hearing loss. Is expressed in several structures, including digestive system; ectoderm; nervous system; neural tube; and pleuroperitoneal region. Orthologous to human GATA3 (GATA binding protein 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
89 figures from 56 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
19 figures from 7 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gata3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypoparathyroidism-deafness-renal disease syndrome Alliance Hypoparathyroidism, sensorineural deafness, and renal dysplasia 146255
Associated With gata3 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000679 Zinc finger, GATA-type
Family IPR016374 Transcription factor, GATA-2/3
Family IPR039355 Transcription factor GATA
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Domain Details Per Protein
Protein Length Transcription factor GATA Transcription factor, GATA-2/3 Zinc finger, GATA-type Zinc finger, NHR/GATA-type
UniProtKB:A0A8M2BC31 384
UniProtKB:Q91428 438
UniProtKB:A0A8M2BC50 403
UniProtKB:B3DGG5 438
UniProtKB:A0A8M9Q5R9 382
UniProtKB:A0A8M2BC08 419
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations