Gene
il4
- ID
- ZDB-GENE-100204-1
- Name
- interleukin 4
- Symbol
- il4 Nomenclature History
- Previous Names
-
- il4/13b (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Acts upstream of or within B cell proliferation; negative regulation of inflammatory response; and regulation of T-helper 2 cell cytokine production. Is expressed in bone tissue; brain; gill; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); hepatitis B; hepatitis C; and pancreatic cancer (multiple). Orthologous to human IL4 (interleukin 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 22 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Bottiglione et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Homologous_superfamily | IPR009079 | Four-helical cytokine-like, core |
Domain Details Per Protein
| Protein | Length | Four-helical cytokine-like, core |
|---|---|---|
|
UniProtKB:D1YSM1
|
127 |
Interactions and Pathways
No data available
Plasmids
No data available