Gene

il1b

ID
ZDB-GENE-040702-2
Name
interleukin 1, beta
Symbol
il1b Nomenclature History
Previous Names
  • zgc:111873
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable cytokine activity. Acts upstream of or within several processes, including fin regeneration; leukocyte chemotaxis; and response to bacterium. Predicted to be located in cytosol; extracellular region; and lysosome. Predicted to be active in extracellular space. Is expressed in several structures, including digestive system; head; heart; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); kidney failure (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to several human genes including IL1B (interleukin 1 beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
235 figures from 168 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With il1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
stomach cancer Alliance {Gastric cancer risk after H. pylori infection} 613659
Associated With il1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020877 Interleukin-1 conserved site
Family IPR000975 Interleukin-1 family
Family IPR003296 Interleukin-1 beta
Homologous_superfamily IPR008996 Cytokine IL1/FGF
Domain Details Per Protein
Protein Length Cytokine IL1/FGF Interleukin-1 beta Interleukin-1 conserved site Interleukin-1 family
UniProtKB:E0WCW4 281
UniProtKB:A0A2R8QPM3 273
UniProtKB:A0A0R4IYF1 284
UniProtKB:Q4KMF1 272
UniProtKB:E6N152 272
UniProtKB:A0A2R8QIV9 272
UniProtKB:Q7T056 273
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab4-il1b Rabbit
1
AB3-il1b monoclonal Mouse
  • IHC
1
Ab1-il1b polyclonal Rabbit
  • IHC
  • WB
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations