Gene

il1b

ID
ZDB-GENE-040702-2
Name
interleukin 1, beta
Symbol
il1b Nomenclature History
Previous Names
  • zgc:111873
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have cytokine activity; interleukin-1 receptor antagonist activity; and interleukin-1 receptor binding activity. Involved in several processes, including fin regeneration; leukocyte chemotaxis; and response to bacterium. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); blood platelet disease (multiple); diabetes mellitus (multiple); eye disease (multiple); and lung disease (multiple). Is expressed in several structures, including brain; liver; male organism; pleuroperitoneal region; and trunk. Orthologous to human IL1B (interleukin 1 beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
287 figures from 212 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With il1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Gastric cancer risk after H. pylori infection} 613659
Associated With il1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020877 Interleukin-1 conserved site
Family IPR000975 Interleukin-1 family
Homologous_superfamily IPR008996 Cytokine IL1/FGF
Domain Details Per Protein
Protein Length Cytokine IL1/FGF Interleukin-1 conserved site Interleukin-1 family
UniProtKB:E6N152 272
UniProtKB:A0A8M1PI54 284
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab4-il1b polyclonal Rabbit
  • WB
1
AB3-il1b monoclonal Mouse
  • IHC
2
Ab1-il1b polyclonal Rabbit
  • IHC
  • WB
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations