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ZIRC
ZFIN ID: ZDB-GENE-051111-1
Gene Name: interleukin 10
Gene Symbol: il10
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: zgc:194510, zgc:194518

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(Including Attributions)
Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cytokine activity. Involved in defense response to bacterium and response to lipopolysaccharide. Predicted to localize to the extracellular region. Human ortholog(s) of this gene  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
e46 Point Mutation Unknown Premature Stop ENU
sa1423 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21894 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44739 Point Mutation Unknown Unknown ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH il10 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    rheumatoid arthritis {Rheumatoid arthritis, progression of} 180300
    {Graft-versus-host disease, protection against} 614395
    {HIV-1, susceptibility to} 609423
    DISEASE ASSOCIATED WITH il10 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to lipopolysaccharide (more)
    Cellular Component extracellular region (more)
    Molecular Function cytokine activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000098 (1)
  • InterPro:IPR009079 (1)
  • InterPro:IPR020443 (1)
  • Pfam:PF00726 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA il10-201 (1) 655
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM il10 No data available
    MARKER RELATIONSHIPS
    il10Contained in: [BAC] CH211-158F7 (1) (order this)
    il10Encodes: [cDNA] MGC:194510 (1) (order this), MGC:194518 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020785 (1) 543bp
    Genomic GenBank:CU459075 (1) 179501bp
    Select Tool
    Polypeptide UniProtKB:Q5EFQ8 (1) 180aa
    Sequence Clusters UniGene:135567 (1)
    Sequence Information (all 18)
    ORTHOLOGY for il10 (Chr: 11)
    CITATIONS (151)