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General Information
ZIRC
ZFIN ID: ZDB-FIG-170517-5
Iklé et al., 2017 - Nkx2.5 regulates Endothelin Converting Enzyme-1 during pharyngeal arch patterning. Genesis (New York, N.Y. : 2000)   55(3) Full text @ Genesis
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage: Prim-5
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Prim-5

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
dlx2a WT standard conditions Prim-5 pharyngeal arch ISH
Prim-5 whole organism RTPCR
WT + MO2-nkx2.5 standard conditions Prim-5 pharyngeal arch ISH
Prim-5 whole organism RTPCR
dlx3b WT standard conditions Prim-5 pharyngeal arch 1 ISH
Prim-5 pharyngeal arch 2 ISH
Prim-5 whole organism RTPCR
WT + MO2-nkx2.5 standard conditions Prim-5 Not Detected pharyngeal arch 1 ISH
Prim-5 Not Detected pharyngeal arch 2 ISH
Prim-5 whole organism RTPCR
dlx5a WT standard conditions Prim-5 pharyngeal arch 1 ISH
Prim-5 pharyngeal arch 2 ISH
Prim-5 whole organism RTPCR
WT + MO2-nkx2.5 standard conditions Prim-5 pharyngeal arch 1 ISH
Prim-5 pharyngeal arch 2 ISH
Prim-5 whole organism RTPCR
dlx6a WT standard conditions Prim-5 pharyngeal arch 1 ISH
Prim-5 pharyngeal arch 2 ISH
Prim-5 whole organism RTPCR
WT + MO2-nkx2.5 standard conditions Prim-5 pharyngeal arch 1 ISH
Prim-5 pharyngeal arch 2 ISH
Prim-5 whole organism RTPCR
ece1 WT standard conditions Prim-5 pharyngeal arch ISH
Prim-5 whole organism RTPCR
WT + MO2-nkx2.5 standard conditions Prim-5 pharyngeal arch ISH
Prim-5 whole organism RTPCR
edn1 WT standard conditions Prim-5 pharyngeal arch ISH
Prim-5 whole organism RTPCR
WT + MO2-nkx2.5 standard conditions Prim-5 pharyngeal arch ISH
Prim-5 whole organism RTPCR
hand2 WT standard conditions Prim-5 pharyngeal arch 1 ISH
Prim-5 pharyngeal arch 2 ISH
Prim-5 pharyngeal arch 3 ISH
Prim-5 pharyngeal arch 4 ISH
Prim-5 whole organism RTPCR
WT + MO2-nkx2.5 standard conditions Prim-5 Not Detected pharyngeal arch 1 ISH
Prim-5 Not Detected pharyngeal arch 2 ISH
Prim-5 pharyngeal arch 3 ISH
Prim-5 pharyngeal arch 4 ISH
Prim-5 whole organism RTPCR
nkx2.7 WT standard conditions Prim-5 whole organism RTPCR
WT + MO2-nkx2.5 standard conditions Prim-5 whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO2-nkx2.5 standard conditions Prim-5 pharyngeal arch edn1 expression decreased distribution, abnormal
Prim-5 pharyngeal arch ece1 expression decreased distribution, abnormal
Prim-5 pharyngeal arch dlx2a expression increased distribution, abnormal
Prim-5 pharyngeal arch 1 dlx3b expression absent, abnormal
Prim-5 pharyngeal arch 1 hand2 expression absent, abnormal
Prim-5 pharyngeal arch 1 dlx6a expression decreased distribution, abnormal
Prim-5 pharyngeal arch 2 dlx3b expression absent, abnormal
Prim-5 pharyngeal arch 2 hand2 expression absent, abnormal
Prim-5 pharyngeal arch 2 dlx6a expression decreased distribution, abnormal
Prim-5 pharyngeal arch 3 hand2 expression decreased distribution, abnormal
Prim-5 pharyngeal arch 4 hand2 expression decreased distribution, abnormal
Prim-5 whole organism dlx6a expression decreased amount, abnormal
Prim-5 whole organism nkx2.7 expression decreased amount, abnormal
Prim-5 whole organism dlx3b expression decreased amount, abnormal
Prim-5 whole organism edn1 expression decreased amount, abnormal
Prim-5 whole organism dlx5a expression decreased amount, abnormal
Full text @ Genesis