ZFIN ID: ZDB-GENE-990415-49
Gene Name: distal-less homeobox 5a
Gene Symbol: dlx5a
Sequence Ontology ID : SO:0000704

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Previous Names: dlx4 (1), zgc:101787

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have sequence-specific DNA binding activity; involved in several processes, including animal organ development, embryonic morphogenesis, and fin development; predicted to localize to the  ...
GENE EXPRESSION
All Expression Data: 82 figures from 37 publications
Directly Submitted Expression Data: 6 figures (15 images) from Thisse et al., 2004 [MGC:101787]
  7 figures (32 images) from Thisse et al., 2005 [eu348]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
j1073aGt Transgenic Insertion Exon 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13174 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39257 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH dlx5a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    split hand-foot malformation 1 with sensorineural hearing loss ?Split-hand/foot malformation 1 with sensorineural hearing loss 220600
    DISEASE ASSOCIATED WITH dlx5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to mechanical stimulus (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000047 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • InterPro:IPR022135 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF12413 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dlx5a-201 (1) 1302
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dlx5a
    MARKER RELATIONSHIPS
    dlx5aContained in: [BAC] CH73-351F10 (1) (order this)
    dlx5aEncodes: [EST] eu348 (1)
    [cDNA] MGC:101787 (1) (order this), MGC:192790 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131306 (1) 1120bp
    Genomic GenBank:CU929240 (1) 96118bp
    Select Tool
    Polypeptide UniProtKB:P50576 (1) 283aa
    Sequence Clusters UniGene:429 (1)
    Sequence Information (all 23)
    OTHER dlx5a GENE PAGES
  • Alliance (1)
  • Gene:30569 (1)
  • VEGA:OTTDARG00000034750 (1)
  • Ensembl(GRCz11):ENSDARG00000042296 (2)
  • ORTHOLOGY for dlx5a (Chr: 19)
    CITATIONS (102)