Gene
dlx5a
- ID
- ZDB-GENE-990415-49
- Name
- distal-less homeobox 5a
- Symbol
- dlx5a Nomenclature History
- Previous Names
-
- dlx4 (1)
- zgc:101787
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including embryonic morphogenesis; fin development; and olfactory nerve formation. Predicted to localize to nuclear chromatin. Is expressed in several structures, including fin; forebrain; pectoral fin bud; pharyngeal arch; and presumptive structure. Human ortholog(s) of this gene implicated in split hand-foot malformation 1 and split hand-foot malformation 1 with sensorineural hearing loss. Orthologous to human DLX5 (distal-less homeobox 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 96 figures from 49 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101787 (15 images)
- eu348 (32 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Distal-less-like homeobox protein, N-terminal domain | Helix-turn-helix motif | Homeobox, conserved site |
---|---|---|---|---|
UniProtKB:P50576
|
283 | |||
UniProtKB:Q5XJL9
|
282 |
Interactions and Pathways
No data available
Plasmids
No data available