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ZIRC
ZFIN ID: ZDB-GENE-061110-100
Gene Name: endothelin converting enzyme 1
Gene Symbol: ece1    Nomenclature History

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Previous Names: fd11b07, wu:fd11b07, zgc:154079

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have metalloendopeptidase activity. Involved in embryonic viscerocranium morphogenesis. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; congestive heart failure; coronary artery disease; essential hypertension; and hypertension. Is expressed in cardiovascular system; fin bud; hindbrain; pharyngeal arch; and somite. Orthologous to human ECE1 (endothelin converting enzyme 1).
Genome Resources: Alliance (1),  Gene:777750 (1),  Ensembl(GRCz11):ENSDARG00000061737 (2)
DISEASE ASSOCIATED WITH ece1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
essential hypertension Alliance {Hypertension, essential, susceptibility to} 145500
?Hirschsprung disease, cardiac defects, and autonomic dysfunction 613870
DISEASE ASSOCIATED WITH ece1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic viscerocranium morphogenesis (more)
Cellular Component integral component of membrane (more)
Molecular Function metalloendopeptidase activity (more)
GO Terms (all 6)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ece1-201 (1)    Ensembl 3293
ece1-202 (1)    Ensembl 525
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ece1 No data available
MARKER RELATIONSHIPS
ece1 Contained in: [BAC] CH211-198P5 (1) (order this), CH211-220M17 (1) (order this)
ece1 Encodes: [EST] fd11b07
[cDNA] MGC:154079 (1) (order this), MGC:192976 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001077792 (1) 2580 bp
Genomic GenBank:BX248318 (1) 194209 bp
Select Tool
Polypeptide UniProtKB:A0JMP1 (1) 752 aa
Sequence Clusters UniGene:79706 (1)
Sequence Information (all 18)
ORTHOLOGY for ece1 ( Chr: 11 )
CITATIONS (18)