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General Information
ZIRC
ZFIN ID: ZDB-GENE-000511-1
Gene Name: heart and neural crest derivatives expressed 2
Gene Symbol: hand2
Sequence Ontology ID : SO:0000704

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Previous Names: dhand (1), han, zdHAND (1), hands off, zgc:103415

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA binding activity and protein dimerization activity; involved in several processes, including animal organ development, determination of intestine left/right asymmetry, and  ...
GENE EXPRESSION
All Expression Data: 152 figures from 103 publications
Directly Submitted Expression Data: 6 figures (17 images) from Thisse et al., 2005 [eu107]
  6 figures (13 images) from Thisse et al., 2005 [eu880]
  6 figures (20 images) from Thisse et al., 2004 [IMAGE:7165464]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
c99 Insertion Unknown Unknown G_RAYS
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ch2Tg Transgenic Insertion 5' UTR Unknown DNA
    hand2_unspecified Unspecified Unknown Unknown
    s40 Unknown Unknown Unknown ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH hand2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hand2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic viscerocranium morphogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598 (1)
  • InterPro:IPR036638 (1)
  • PROSITE:PS50888 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hand2-201 (1) 1641
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    MARKER RELATIONSHIPS
    hand2Contained in: [BAC] CH211-15E22 (1) (order this)
    hand2Encodes: [EST] eu107 (1), eu880 (1), IMAGE:7165464 (1) (order this)
    [cDNA] MGC:103415 (1) (order this), MGC:192190 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131626 (1) 1668bp
    Genomic GenBank:BX000460 (1) 173084bp
    Select Tool
    Polypeptide UniProtKB:P57102 (1) 208aa
    Sequence Clusters UniGene:81423 (1)
    Sequence Information (all 21)
    ORTHOLOGY for hand2 (Chr: 1)
    CITATIONS (215)