ZFIN ID: ZDB-GENE-980526-212
Gene Name: distal-less homeobox 2a
Gene Symbol: dlx2a
Sequence Ontology ID : SO:0000704

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Previous Names: dlx-2, dlx2, zgc:110518

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 346 figures from 241 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2005 [eu96]
  12 figures (14 images) from Rauch et al., 2003 [fc28e03]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
  anatomical structure, anguloarticular, apical ectodermal ridge pectoral fin bud, brain (all 136) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11175 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-dlx2a (1), MO2-dlx2a (1)
    PHENOTYPE
    Data: 3 figures from Sperber et al., 2008
    Observed in: ceratobranchial cartilage chondrocyte, ceratohyal cartilage, cranial neural crest, ethmoid cartilage (all 10) expand
    DISEASE ASSOCIATED WITH dlx2a HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cartilage development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000047 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • InterPro:IPR022135 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF12413 (1)
  •  Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dlx2a
    Tg(dlx1aIG:GFP), Tg(dlx1aURE2:GFP)
    MARKER RELATIONSHIPS
    dlx2aContained in: [BAC] CH211-245G15 (1) (order this)
    dlx2aEncodes: [EST] eu96 (1), fc28e03 (1) (order this)
    [cDNA] MGC:110518 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131311 (1) 1668bp
    Genomic GenBank:BX248116 (1) 161065bp
    Select Tool
    Polypeptide UniProtKB:F6NKE2 (1) 274aa
    Sequence Clusters UniGene:2 (1)
    Sequence Information (all 18)
    OTHER dlx2a GENE PAGES
  • Alliance (1)
  • Gene:30574 (1)
  • Ensembl(GRCz10):ENSDARG00000079964 (1)
  • ORTHOLOGY for dlx2a (Chr: 9)
    CITATIONS (367)