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General Information
ZIRC
ZFIN ID: ZDB-FISH-150901-12821
Fish name: WT + MO2-nkx2.5
Genotype: WT
Targeting Reagent: MO2-nkx2.5
HUMAN DISEASE MODELED by WT + MO2-nkx2.5
No data available
GENE EXPRESSION
Gene expression in WT + MO2-nkx2.5
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab-S46 standard conditions Fig. 1 with image from Targoff et al., 2008
Ab-MF20 standard conditions Fig. 1 with image from Targoff et al., 2008
Reporter gene expression No data available
PHENOTYPE
Phenotype in WT + MO2-nkx2.5
Phenotype Conditions Figures
atrium shape, abnormal standard conditions Fig. 1 with image from Targoff et al., 2008
basihyal cartilage decreased size, abnormal standard conditions Fig. 5 from Iklé et al., 2017
cardiac ventricle decreased size, abnormal standard conditions Fig. 1 with image from Targoff et al., 2008
ceratobranchial cartilage hypoplastic, abnormal standard conditions Fig. 5 from Iklé et al., 2017
cranial cartilage hypoplastic, abnormal standard conditions Fig. 5Fig. 7 from Iklé et al., 2017
hyosymplectic cartilage hypoplastic, abnormal standard conditions Fig. 5 from Iklé et al., 2017
Meckel's cartilage curved ventral, abnormal standard conditions Fig. 5Fig. 7 from Iklé et al., 2017
palatoquadrate cartilage malformed, abnormal standard conditions Fig. 5 from Iklé et al., 2017
pharyngeal arch ece1 expression decreased distribution, abnormal standard conditions Fig. 6 from Iklé et al., 2017
pharyngeal arch edn1 expression decreased distribution, abnormal standard conditions Fig. 6 from Iklé et al., 2017
pharyngeal arch hand2 expression decreased distribution, abnormal standard conditions Fig. 7 from Iklé et al., 2017
pharyngeal arch dlx2a expression increased distribution, abnormal standard conditions Fig. 6 from Iklé et al., 2017
pharyngeal arch 1 dlx3b expression absent, abnormal standard conditions Fig. 6 from Iklé et al., 2017
pharyngeal arch 1 hand2 expression absent, abnormal standard conditions Fig. 6 from Iklé et al., 2017
pharyngeal arch 1 dlx6a expression decreased distribution, abnormal standard conditions Fig. 6 from Iklé et al., 2017
pharyngeal arch 2 hand2 expression absent, abnormal standard conditions Fig. 6 from Iklé et al., 2017
pharyngeal arch 2 dlx3b expression absent, abnormal standard conditions Fig. 6 from Iklé et al., 2017
pharyngeal arch 2 dlx6a expression decreased distribution, abnormal standard conditions Fig. 6 from Iklé et al., 2017
pharyngeal arch 3 hand2 expression decreased distribution, abnormal standard conditions Fig. 6 from Iklé et al., 2017
pharyngeal arch 4 hand2 expression decreased distribution, abnormal standard conditions Fig. 6 from Iklé et al., 2017
whole organism dlx5a expression decreased amount, abnormal standard conditions Fig. 6 from Iklé et al., 2017
whole organism edn1 expression decreased amount, abnormal standard conditions Fig. 6 from Iklé et al., 2017
whole organism dlx6a expression decreased amount, abnormal standard conditions Fig. 6 from Iklé et al., 2017
whole organism dlx3b expression decreased amount, abnormal standard conditions Fig. 6 from Iklé et al., 2017
whole organism nkx2.7 expression decreased amount, abnormal standard conditions Fig. 6 from Iklé et al., 2017

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