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ZFIN ID: ZDB-FIG-120810-47
Hutchinson et al., 2012 - Tbl3 regulates cell cycle length during zebrafish development. Developmental Biology   368(2):261-272 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Long-pec to Protruding-mouth

Fig. S1 Tissue specification and patterning is normal in cey mutants

Despite the severe reduction of HSPCs in cey mutants at 4 dpf, HSPCs labeled by c-myb in cey mutants at 2 dpf are comparable to wild-type (A, B). The cranial neural crest labeled by dlx2a gives rise to jaw cartilage and is normal at 2 dpf in cey mutants (C, D). At 3 dpf the endoderm that contributes to jaw formation is specified properly as indicated by nkx2.3 staining in cey mutants (E, F). Patterning and size of the intestinal and pancreatic anlage is also normal as shown by gata6 staining in cey mutants at 3 dpf (G, H). While differentiation of the exocrine pancreas is deficient, beta cells in the endocrine pancreas labeled by insulin are normal in cey mutants at 3 dpf (I, J). Scale bars are 125 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
dlx2a WT standard conditions Long-pec mandibular arch skeleton ISH
tbl3Df(Chr03:noxo1a,zgc:113100,sox8b,proza)cz26/cz26 standard conditions Long-pec mandibular arch skeleton ISH
gata6 WT standard conditions Protruding-mouth intestine ISH
Protruding-mouth pancreas ISH
tbl3Df(Chr03:noxo1a,zgc:113100,sox8b,proza)cz26/cz26 standard conditions Protruding-mouth intestine ISH
Protruding-mouth pancreas ISH
ins WT standard conditions Protruding-mouth endocrine pancreas ISH
tbl3Df(Chr03:noxo1a,zgc:113100,sox8b,proza)cz26/cz26 standard conditions Protruding-mouth endocrine pancreas ISH
myb WT standard conditions Long-pec hematopoietic stem cell ISH
tbl3Df(Chr03:noxo1a,zgc:113100,sox8b,proza)cz26/cz26 standard conditions Long-pec hematopoietic stem cell ISH
nkx2.3 WT standard conditions Protruding-mouth pharyngeal pouch ISH
tbl3Df(Chr03:noxo1a,zgc:113100,sox8b,proza)cz26/cz26 standard conditions Protruding-mouth pharyngeal pouch ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 368(2), Hutchinson, S.A., Tooke-Locke, E., Wang, J., Tsai, S., Katz, T., and Trede, N.S., Tbl3 regulates cell cycle length during zebrafish development, 261-272, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.