Gene

myb

ID
ZDB-GENE-991110-14
Name
v-myb avian myeloblastosis viral oncogene homolog
Symbol
myb Nomenclature History
Previous Names
  • c-myb
  • cmyb
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including definitive hemopoiesis; hematopoietic stem cell migration; and regulation of neutrophil differentiation. Localizes to chromatin. Is expressed in several structures, including head; hematopoietic cell; hematopoietic system; mesoderm; and vasculature. Orthologous to human MYB (MYB proto-oncogene, transcription factor).
Genome Resources
Note
None
Expression
All Expression Data
392 figures from 188 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
21 figures from 9 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With myb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{T-cell acute lymphoblastic leukemia}
Associated With myb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001005 SANT/Myb domain
Domain IPR012642 Transcription regulator Wos2-domain
Domain IPR015395 C-myb, C-terminal
Domain IPR017930 Myb domain
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length C-myb, C-terminal Homeobox-like domain superfamily Myb domain SANT/Myb domain Transcription regulator Wos2-domain
UniProtKB:A0A2R8Q8E3 641
UniProtKB:F1QP24 641
UniProtKB:F1QP25 590
UniProtKB:A0A2R8RYE8 590
UniProtKB:Q9PTJ4 590
UniProtKB:Q6PBA4 641
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cmyb monoclonal IgG2a Mouse
  • WB
Bio-Rad AbD Serotec
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations