ZFIN ID: ZDB-GENE-980526-110
Gene Name: preproinsulin
Gene Symbol: ins
Sequence Ontology ID : SO:0000704

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Previous Names: insa (1), zgc:109842

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 287 figures from 163 publications
Directly Submitted Expression Data: 7 figures (9 images) from Thisse et al., 2004 [MGC:109842]
Wild-type Stages, Structures: Segmentation:10-13 somites (14.0h-16.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns102 Small Deletion Unknown Unknown CRISPR
Targeting reagents:
PHENOTYPE
Data: 8 figures from 3 publications
Observed in:
DISEASE ASSOCIATED WITH ins HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
maturity-onset diabetes of the young type 10 Maturity-onset diabetes of the young, type 10 613370
permanent neonatal diabetes mellitus Diabetes mellitus, permanent neonatal 606176
type 1 diabetes mellitus 2 Diabetes mellitus, insulin-dependent, 2 125852
Hyperproinsulinemia 616214
DISEASE ASSOCIATED WITH ins VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to glucose (more)
Cellular Component extracellular region (more)
Molecular Function hormone activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004825 (1)
  • InterPro:IPR016179 (1)
  • InterPro:IPR022352 (1)
  • InterPro:IPR022353 (1)
  • InterPro:IPR036438 (1)
  • PROSITE:PS00262 (1)
  • Pfam:PF00049 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000061776 (1) 485
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ins
    MARKER RELATIONSHIPS
    insContained in: [BAC] CH211-69I14 (1) (order this), CH211-139A5 (1) (order this)
    insEncodes: [cDNA] MGC:109842 (1) (order this), MGC:192614 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131056 (1) 468bp
    Genomic GenBank:AL935065 (1) 167740bp
    Select Tool
    Polypeptide UniProtKB:B2GSI0 (1) 108aa
    Sequence Clusters UniGene:75811 (1)
    Sequence Information (all 21)
    OTHER ins GENE PAGES
  • Alliance (1)
  • Gene:30262 (1)
  • VEGA:OTTDARG00000042752 (1)
  • ORTHOLOGY for ins (Chr: 5)
    CITATIONS (287)