Morpholino

MO1-gata6

ID

ZDB-MRPHLNO-050927-1

Name

MO1-gata6

Previous Names

zfMDL MO (1)

Target

gata6 (1)

Sequence

5' - AGCTGTTATCACCCAGGTCCATCCA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

The sequence reported in Peterkin et al, 2003 is written 3' -> 5'. The sequence shown has been reversed.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-gata6

Expressed Gene	Anatomy	Figures
bmp4	gut	Fig. 6 from Zeng et al., 2012
cp	hepatocyte	Fig. 5 from Shin et al., 2007
egr2b	presumptive rhombomere 3 presumptive rhombomere 5 rhombomere 3 rhombomere 5	Fig. 5 , Fig. 6 from Peterkin et al., 2007
foxa2	margin	Fig. 3 from Tseng et al., 2011
foxa3	whole organism	Fig. 3 from Tseng et al., 2011
foxb1a	DEL	Fig. 2 from Tseng et al., 2011
gata4	heart primordium lateral mesoderm	Fig. 5 , Fig. 6 from Peterkin et al., 2007 Fig. 8 from Peterkin et al., 2003
gata5	DEL lateral mesoderm yolk syncytial layer	Fig. 3 from Tseng et al., 2011 Fig. 8 from Peterkin et al., 2003
hhex	liver pancreatic bud	Fig. 5 from Shin et al., 2007
ihha	gut	Fig. 6 from Zeng et al., 2012
myh6	heart tube	Fig. 3 from Holtzinger et al., 2007
myh7	heart tube presumptive cardiac ventricle heart tube	Fig. 4 from Holtzinger et al., 2007 Fig. 4 from Peterkin et al., 2007 Fig. 8 from Peterkin et al., 2003
myl7	heart tube presumptive cardiac ventricle heart tube primitive heart tube	Fig. 4 from Peterkin et al., 2007 Fig. 8 from Peterkin et al., 2003
myod1	somite	Fig. 5 , Fig. 6 from Peterkin et al., 2007
nkx2.5	heart primordium heart tube lateral mesoderm primitive heart tube	Fig. 5 from Holtzinger et al., 2007 Fig. 4 , Fig. 5 , Fig. 6 from Peterkin et al., 2007 Fig. 8 from Peterkin et al., 2003
prox1a	interrenal primordium liver	Fig. 5 from Shin et al., 2007
sebox	presumptive endoderm	Fig. 3 from Tseng et al., 2011
shha	gut	Fig. 6 from Zeng et al., 2012
sox32	presumptive endoderm	Fig. 2 , Fig. 3 from Tseng et al., 2011
tbx16	presumptive mesoderm	Fig. 3 from Tseng et al., 2011
tfa	whole organism	Fig. 7 from Holtzinger et al., 2005

Phenotype

Phenotype resulting from MO1-gata6

Phenotype	Fish	Figures
cell population proliferation increased rate, abnormal	TL + MO1-gata6	Fig. 6 from Zeng et al., 2012
embryonic heart tube development disrupted, abnormal	WT + MO1-gata6	Fig. 4 , Fig. 5 from Peterkin et al., 2007
gut immature, abnormal	TL + MO1-gata6	Fig. 6 from Zeng et al., 2012
heart hypoplastic, abnormal	twu34Tg + MO1-gata6	Fig. S4 from Gupta et al., 2013
heart morphogenesis decreased process quality, abnormal	twu34Tg + MO1-gata6	Fig. S4 from Gupta et al., 2013
heart morphogenesis disrupted, abnormal	WT + MO1-gata6	Fig. 4 , Fig. 5 from Peterkin et al., 2007
heart morphogenesis process quality, abnormal	knu9Tg + MO1-gata6 (AB)	Fig. 2 from Park et al., 2009
heart tube malformed, abnormal	WT + MO1-gata6	Fig. 4 , Fig. 5 from Peterkin et al., 2007

Phenotype of all Fish created by or utilizing MO1-gata6

Phenotype	Fish	Conditions	Figures
cell population proliferation increased rate, abnormal	TL + MO1-gata6	standard conditions	Fig. 6 from Zeng et al., 2012
gut immature, abnormal	TL + MO1-gata6	standard conditions	Fig. 6 from Zeng et al., 2012
heart tube malformed, abnormal	WT + MO1-gata6	standard conditions	Fig. 4 , Fig. 5 from Peterkin et al., 2007
embryonic heart tube development disrupted, abnormal	WT + MO1-gata6	standard conditions	Fig. 4 , Fig. 5 from Peterkin et al., 2007
heart morphogenesis disrupted, abnormal	WT + MO1-gata6	standard conditions	Fig. 4 , Fig. 5 from Peterkin et al., 2007
heart morphogenesis process quality, abnormal	knu9Tg + MO1-gata6 (AB)	standard conditions	Fig. 2 from Park et al., 2009
heart hypoplastic, abnormal	twu34Tg + MO1-gata6	standard conditions	Fig. S4 from Gupta et al., 2013
heart morphogenesis decreased process quality, abnormal	twu34Tg + MO1-gata6	standard conditions	Fig. S4 from Gupta et al., 2013
heart morphogenesis disrupted, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. 4 , Fig. 5 from Peterkin et al., 2007
heart formation disrupted, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. 3 from Peterkin et al., 2009
otic placode foxj1b expression decreased amount, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. S3 from Jia et al., 2018
embryonic heart tube development disrupted, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. 4 , Fig. 5 from Peterkin et al., 2007
fin bud aplastic, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. 6 from Peterkin et al., 2009
whole organism mir210 expression increased amount, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. 2 from Jia et al., 2018
yolk syncytial layer slc3a2a expression decreased amount, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. S3 from Jia et al., 2018
granulocyte mpx expression decreased amount, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. 3 from Jia et al., 2018
cardioblast migration to the midline involved in heart field formation disrupted, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. 3 from Peterkin et al., 2009
myeloid cell differentiation disrupted, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. 1 from Peterkin et al., 2009
myeloid cell differentiation decreased occurrence, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. 3 from Jia et al., 2018
heart tube malformed, abnormal	WT + MO1-gata5 + MO1-gata6	standard conditions	Fig. 4 , Fig. 5 from Peterkin et al., 2007
anterior lateral plate mesoderm physical object quality, abnormal	WT + MO1-gata6 + MO2-gata5	standard conditions	Fig. 2 from Novikov et al., 2013
heart tube malformed, abnormal	WT + MO1-gata6 + MO3-gata4	standard conditions	Fig. 4 , Fig. 5 from Peterkin et al., 2007
embryonic heart tube development disrupted, abnormal	WT + MO1-gata6 + MO3-gata4	standard conditions	Fig. 4 , Fig. 5 from Peterkin et al., 2007
heart morphogenesis disrupted, abnormal	WT + MO1-gata6 + MO3-gata4	standard conditions	Fig. 4 , Fig. 5 from Peterkin et al., 2007
otic placode foxj1b expression amount, ameliorated	mir210^nju49/nju49 + MO1-gata5 + MO1-gata6	standard conditions	Fig. S3 from Jia et al., 2018
granulocyte mpx expression amount, ameliorated	mir210^nju49/nju49 + MO1-gata5 + MO1-gata6	standard conditions	Fig. 3 from Jia et al., 2018
myeloid cell differentiation occurrence, ameliorated	mir210^nju49/nju49 + MO1-gata5 + MO1-gata6	standard conditions	Fig. 3 from Jia et al., 2018
yolk syncytial layer slc3a2a expression amount, ameliorated	mir210^nju49/nju49 + MO1-gata5 + MO1-gata6	standard conditions	Fig. S3 from Jia et al., 2018
margin EGFP expression absent, abnormal	hsc70Tg + MO1-gata5 + MO1-gata6	standard conditions	Fig. 2 from Yuan et al., 2018
lateral mesoderm EGFP expression decreased amount, abnormal	hsc70Tg + MO1-gata5 + MO1-gata6	standard conditions	Fig. 2 from Yuan et al., 2018
cardiac ventricle EGFP expression decreased distribution, abnormal	knu9Tg + MO1-gata6 + MO5-gata4 (AB)	standard conditions	Fig. 6 from Park et al., 2009
heart physical object quality, abnormal	twu34Tg + MO1-gata5 + MO1-gata6	standard conditions	Fig. 2 from Holtzinger et al., 2007
cardiac muscle cell decreased amount, abnormal	twu34Tg + MO1-gata5 + MO1-gata6	standard conditions	Fig. 2 from Holtzinger et al., 2007
heart primordium left side unfused from heart primordium right side, abnormal	twu34Tg + MO1-gata6 + MO2-gata4	standard conditions	Fig. 2 from Holtzinger et al., 2007
heart bifurcated, abnormal	twu34Tg + MO1-gata6 + MO2-gata4	standard conditions	Fig. 2 from Holtzinger et al., 2007
heart physical object quality, abnormal	twu34Tg + MO1-gata6 + MO2-gata4	standard conditions	Fig. 2 from Holtzinger et al., 2007
heart absent, abnormal	knu9Tg + MO1-gata5 + MO1-gata6 + MO5-gata4 (AB)	standard conditions	Fig. 6 from Park et al., 2009
whole organism EGFP expression absent, abnormal	knu9Tg + MO1-gata5 + MO1-gata6 + MO5-gata4 (AB)	standard conditions	Fig. 6 from Park et al., 2009

Citations