Figure 3—figure supplement 3.

Phenotypic analysis of dt-runx1 expressing mutants: expansion of the thymus.

(A) 3D-rendering of confocal spinning disk sections of the thymus region of 5 dpf Tg(kdrl:gal4;UAS:RFP) (left, control) and incrossed Tg(kdrl:Gal4;UAS:RFP;4xNR:dt-runx1-eGFP) (right, dt-runx1) larva. Thymic cells have been individually segmented. Scale bars = 10 µm. (B) Morphometric analysis of the thymus. Left: thymic volume (in µm3, corresponding to the sum of all thymic cell volumes). Center: cell count. Right: thymic cells volume (in µm3). Statistical comparisons have been performed using two-sided unpaired Wilcoxon tests, all p-values are displayed. Analysis was carried out on n=5 control embryos and n=5 mutant embryos.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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