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ZFIN ID: ZDB-FIG-200806-2
Espín-Palazón et al., 2014 - Proinflammatory signaling regulates hematopoietic stem cell emergence. Cell   159:1070-85 Full text @ Cell
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-5 to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Long-pec to Protruding-mouth

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
dlc WT standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
WT + MO2-tnfrsf1b standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
WT + MO4-tnfa standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
efnb2a WT standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
WT + MO2-tnfrsf1b standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
WT + MO4-tnfa standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
EGFP la2Tg; sd2Tg standard conditions Protruding-mouth caudal hematopoietic tissue hematopoietic multipotent progenitor cell IFL
la2Tg; sd2Tg + MO2-tnfrsf1b standard conditions Protruding-mouth Not Detected caudal hematopoietic tissue hematopoietic multipotent progenitor cell IFL
la2Tg; sd2Tg + MO4-tnfa standard conditions Protruding-mouth Not Detected caudal hematopoietic tissue hematopoietic multipotent progenitor cell IFL
nkuasrfp1aTg; ubs4Tg; ums1Tg; zf169Tg standard conditions Long-pec ventral wall of dorsal aorta IFL
Long-pec ventral wall of dorsal aorta hematopoietic stem cell IFL
nkuasrfp1aTg; ubs4Tg; zf169Tg standard conditions Long-pec ventral wall of dorsal aorta hematopoietic stem cell IFL
kdrl WT standard conditions Prim-5 endothelial cell ISH
WT + MO2-tnfrsf1b standard conditions Prim-5 endothelial cell ISH
WT + MO4-tnfa standard conditions Prim-5 endothelial cell ISH
notch1b WT standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
WT + MO2-tnfrsf1b standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
WT + MO4-tnfa standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
notch3 WT standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
WT + MO2-tnfrsf1b standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
WT + MO4-tnfa standard conditions Prim-5 artery ISH
Prim-5 caudal artery ISH
RFP la2Tg; sd2Tg standard conditions Protruding-mouth nucleate erythrocyte IFL
la2Tg; sd2Tg + MO2-tnfrsf1b standard conditions Protruding-mouth nucleate erythrocyte IFL
la2Tg; sd2Tg + MO4-tnfa standard conditions Protruding-mouth nucleate erythrocyte IFL
nkuasrfp1aTg; ubs4Tg; ums1Tg; zf169Tg standard conditions Long-pec endothelial cell IFL
Long-pec ventral wall of dorsal aorta hematopoietic stem cell IFL
nkuasrfp1aTg; ubs4Tg; zf169Tg standard conditions Long-pec endothelial cell IFL
Long-pec ventral wall of dorsal aorta hematopoietic stem cell IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
la2Tg; sd2Tg + MO2-tnfrsf1b standard conditions Protruding-mouth caudal hematopoietic tissue hematopoietic multipotent progenitor cell decreased amount, abnormal
Protruding-mouth caudal hematopoietic tissue hematopoietic multipotent progenitor cell EGFP expression absent, abnormal
la2Tg; sd2Tg + MO4-tnfa standard conditions Protruding-mouth caudal hematopoietic tissue hematopoietic multipotent progenitor cell decreased amount, abnormal
Protruding-mouth caudal hematopoietic tissue hematopoietic multipotent progenitor cell EGFP expression absent, abnormal
nkuasrfp1aTg; ubs4Tg; ums1Tg; zf169Tg standard conditions Long-pec ventral wall of dorsal aorta EGFP expression increased distribution, abnormal
Long-pec ventral wall of dorsal aorta hematopoietic stem cell increased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Cell for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Cell, 159, Espín-Palazón, R., Stachura, D.L., Campbell, C.A., García-Moreno, D., Del Cid, N., Kim, A.D., Candel, S., Meseguer, J., Mulero, V., Traver, D., Proinflammatory signaling regulates hematopoietic stem cell emergence, 1070-85, Copyright (2014) with permission from Elsevier. Full text @ Cell