ZFIN ID: ZDB-FIG-171220-3
Kwan et al., 2016 - The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. Cell Stem Cell   19:370-82 Full text @ Cell Stem Cell
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-5 to Prim-15
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Long-pec

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
crhr1 WT chemical treatment by environment: cobalt dichloride Prim-15 whole organism RTPCR
EGFP sh144Tg control Prim-5 brain ISH
Prim-15 brain ISH
sh144Tg chemical treatment by environment: cobalt dichloride Prim-5 brain ISH
Prim-15 brain ISH
nr3c1 WT chemical treatment by environment: cobalt dichloride Prim-15 whole organism RTPCR
pomca WT chemical treatment by environment: cobalt dichloride Prim-15 whole organism RTPCR
pomcb WT chemical treatment by environment: cobalt dichloride Prim-15 whole organism RTPCR
runx1 WT control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT chemical treatment by environment: cobalt dichloride Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO2-tph2 control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO2-tph2 chemical treatment by environment: cobalt dichloride Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO5-nr3c1 control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO5-nr3c1 chemical treatment by environment: cobalt dichloride Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
tph2 WT chemical treatment by environment: cobalt dichloride Prim-15 whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment by environment: cobalt dichloride Prim-15 anatomical structure cortisol increased amount, abnormal
Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression increased amount, abnormal
Prim-15 whole organism crhr1 expression increased amount, abnormal
Prim-15 whole organism nr3c1 expression increased amount, abnormal
Prim-15 whole organism pomca expression increased amount, abnormal
Prim-15 whole organism pomcb expression increased amount, abnormal
Prim-15 whole organism tph2 expression increased amount, abnormal
WT + MO2-tph2 control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO2-tph2 chemical treatment by environment: cobalt dichloride Prim-15 anatomical structure cortisol amount, ameliorated
Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO5-nr3c1 control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO5-nr3c1 chemical treatment by environment: cobalt dichloride Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
pd27Tg; zf169Tg chemical treatment by environment: cobalt dichloride Long-pec hematopoietic multipotent progenitor cell increased amount, abnormal
pd27Tg; zf169Tg + MO2-tph2 control Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO2-tph2 chemical treatment by environment: cobalt dichloride Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO5-nr3c1 control Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO5-nr3c1 chemical treatment by environment: cobalt dichloride Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
sh144Tg chemical treatment by environment: cobalt dichloride Prim-5 brain EGFP expression increased amount, abnormal
Prim-15 brain EGFP expression increased amount, abnormal
Full text @ Cell Stem Cell