Gene

crhr1

ID
ZDB-GENE-081231-1
Name
corticotropin releasing hormone receptor 1
Symbol
crhr1 Nomenclature History
Previous Names
  • crfr1 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have corticotrophin-releasing factor receptor activity; corticotropin-releasing hormone receptor activity; and peptide hormone binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and obesity. Is expressed in griseum centrale and hindbrain. Orthologous to several human genes including LINC02210-CRHR1 (LINC02210-CRHR1 readthrough).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With crhr1 Human Ortholog
No data available
Associated With crhr1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017983 GPCR, family 2, secretin-like, conserved site
Domain IPR001879 GPCR, family 2, extracellular hormone receptor domain
Domain IPR017981 GPCR, family 2-like
Family IPR000832 GPCR, family 2, secretin-like
Family IPR003051 GPCR, family 2, corticotropin releasing factor receptor
Family IPR003052 GPCR, family 2, corticotropin releasing factor receptor, type 1
Homologous_superfamily IPR036445 GPCR family 2, extracellular hormone receptor domain superfamily
Domain Details Per Protein
Protein Length GPCR, family 2, corticotropin releasing factor receptor GPCR, family 2, corticotropin releasing factor receptor, type 1 GPCR, family 2, extracellular hormone receptor domain GPCR family 2, extracellular hormone receptor domain superfamily GPCR, family 2-like GPCR, family 2, secretin-like GPCR, family 2, secretin-like, conserved site
UniProtKB:X1WHD4 430
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations