ZFIN ID: ZDB-FIG-171220-1
Kwan et al., 2016 - The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. Cell Stem Cell   19:370-82 Full text @ Cell Stem Cell
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Conditions:
Anatomical Terms:
Stage Range: Prim-15 to Protruding-mouth
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage Range: Prim-15 to Protruding-mouth

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
crhr1 WT chemical treatment by environment: serotonin Prim-15 whole organism RTPCR
myb WT control Protruding-mouth hematopoietic multipotent progenitor cell ISH
WT chemical treatment by environment: dexamethasone Protruding-mouth hematopoietic multipotent progenitor cell ISH
Protruding-mouth whole organism RTPCR
WT chemical treatment by environment: cortisol Protruding-mouth hematopoietic multipotent progenitor cell ISH
Protruding-mouth whole organism RTPCR
nr3c1 WT chemical treatment by environment: serotonin Prim-15 whole organism RTPCR
pomca WT chemical treatment by environment: serotonin Prim-15 whole organism RTPCR
pomcb WT chemical treatment by environment: serotonin Prim-15 whole organism RTPCR
runx1 WT control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT chemical treatment by environment: dexamethasone Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT chemical treatment by environment: cortisol Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment by environment: dexamethasone Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression increased amount, abnormal
Protruding-mouth hematopoietic multipotent progenitor cell myb expression increased amount, abnormal
Protruding-mouth hematopoietic multipotent progenitor cell myb expression increased distribution, abnormal
Protruding-mouth whole organism myb expression increased amount, abnormal
WT chemical treatment by environment: cortisol Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression increased amount, abnormal
Protruding-mouth hematopoietic multipotent progenitor cell myb expression increased amount, abnormal
Protruding-mouth hematopoietic multipotent progenitor cell myb expression increased distribution, abnormal
Protruding-mouth whole organism myb expression increased amount, abnormal
WT chemical treatment by environment: serotonin Prim-15 anatomical structure cortisol increased amount, abnormal
Prim-15 whole organism crhr1 expression increased amount, abnormal
Prim-15 whole organism nr3c1 expression increased amount, abnormal
Prim-15 whole organism pomca expression increased amount, abnormal
Prim-15 whole organism pomcb expression increased amount, abnormal
pd27Tg; zf169Tg chemical treatment by environment: dexamethasone Long-pec hematopoietic multipotent progenitor cell increased amount, abnormal
pd27Tg; zf169Tg chemical treatment by environment: cortisol Long-pec hematopoietic multipotent progenitor cell increased amount, abnormal
Full text @ Cell Stem Cell