ZFIN ID: ZDB-FIG-171219-7
Kwan et al., 2016 - The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. Cell Stem Cell   19:370-82 Full text @ Cell Stem Cell
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Conditions:
Anatomical Terms:
Stage Range: Protruding-mouth to Day 5
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: Protruding-mouth to Day 5

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
myb WT control Protruding-mouth hematopoietic multipotent progenitor cell ISH
WT chemical treatment by environment: metronidazole Protruding-mouth hematopoietic multipotent progenitor cell ISH
y226Tg control Protruding-mouth hematopoietic multipotent progenitor cell ISH
y226Tg chemical ablation: serotonergic neuron, chemical treatment by environment: metronidazole Protruding-mouth hematopoietic multipotent progenitor cell ISH
Protruding-mouth whole organism RTPCR
rag2 WT control Day 5 thymus T cell ISH
WT chemical treatment by environment: metronidazole Day 5 thymus T cell ISH
y226Tg control Day 5 thymus T cell ISH
y226Tg chemical ablation: serotonergic neuron, chemical treatment by environment: metronidazole Day 5 thymus T cell ISH
Day 5 whole organism RTPCR
tph2 y226Tg control Protruding-mouth serotonergic neuron ISH
y226Tg chemical ablation: serotonergic neuron, chemical treatment by environment: metronidazole Protruding-mouth Not Detected serotonergic neuron ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
y226Tg chemical ablation: serotonergic neuron, chemical treatment by environment: metronidazole Protruding-mouth hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal
Protruding-mouth hematopoietic multipotent progenitor cell myb expression decreased distribution, abnormal
Protruding-mouth hematopoietic multipotent progenitor cell decreased amount, abnormal
Protruding-mouth serotonergic neuron tph2 expression absent, abnormal
Protruding-mouth serotonergic neuron absent, abnormal
Protruding-mouth whole organism myb expression decreased amount, abnormal
Day 5 thymus T cell rag2 expression decreased amount, abnormal
Day 5 thymus T cell decreased amount, abnormal
Day 5 whole organism rag2 expression decreased amount, abnormal
Full text @ Cell Stem Cell