ZFIN ID: ZDB-FIG-171219-6
Kwan et al., 2016 - The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. Cell Stem Cell   19:370-82 Full text @ Cell Stem Cell
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-15 to Long-pec
PHENOTYPE:
Fish:
Conditions:
Knockdown Reagents:
Observed In:
Stage Range: Prim-15 to Long-pec

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
myb WT control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Long-pec hematopoietic multipotent progenitor cell ISH
WT chemical treatment by environment: 4-chloro-L-phenylalanine Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO1-tph1a standard conditions Long-pec hematopoietic multipotent progenitor cell ISH
WT + MO1-tph1a + MO1-tph1b standard conditions Long-pec hematopoietic multipotent progenitor cell ISH
WT + MO1-tph1a + MO1-tph1b + MO2-tph2 standard conditions Long-pec hematopoietic multipotent progenitor cell ISH
WT + MO1-tph1b standard conditions Long-pec hematopoietic multipotent progenitor cell ISH
WT + MO2-tph2 standard conditions Long-pec hematopoietic multipotent progenitor cell ISH
runx1 WT control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT chemical treatment by environment: 4-chloro-L-phenylalanine Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO1-tph1a standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO1-tph1a + MO1-tph1b standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO1-tph1a + MO1-tph1b + MO2-tph2 standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO1-tph1b standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO2-tph2 standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment by environment: 4-chloro-L-phenylalanine Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal
Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO1-tph1a standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO1-tph1a + MO1-tph1b standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
Long-pec hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal
Long-pec hematopoietic multipotent progenitor cell myb expression decreased distribution, abnormal
WT + MO1-tph1a + MO1-tph1b + MO2-tph2 standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
Long-pec hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal
Long-pec hematopoietic multipotent progenitor cell myb expression decreased distribution, abnormal
WT + MO1-tph1b standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
Long-pec hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal
Long-pec hematopoietic multipotent progenitor cell myb expression decreased distribution, abnormal
WT + MO2-tph2 standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
Long-pec hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal
Long-pec hematopoietic multipotent progenitor cell myb expression decreased distribution, abnormal
la2Tg + MO1-tph1a + MO1-tph1b + MO2-tph2 standard conditions Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
la2Tg + MO2-tph2 standard conditions Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg chemical treatment by environment: 4-chloro-L-phenylalanine Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg chemical treatment by environment: serotonin Long-pec hematopoietic multipotent progenitor cell increased amount, abnormal
pd27Tg; zf169Tg + MO1-tph1a + MO1-tph1b + MO2-tph2 standard conditions Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO2-tph2 control Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO2-tph2 standard conditions Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO2-tph2 chemical treatment by environment: serotonin Long-pec hematopoietic multipotent progenitor cell amount, ameliorated
Full text @ Cell Stem Cell