ZFIN ID: ZDB-FIG-171220-2
Kwan et al., 2016 - The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. Cell Stem Cell   19:370-82 Full text @ Cell Stem Cell
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Conditions:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-15 to Day 5
PHENOTYPE:
Fish:
Conditions:
Knockdown Reagents:
Observed In:
Stage Range: Prim-15 to Day 5

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP la2Tg control Long-pec hematopoietic multipotent progenitor cell IFL
myb WT standard conditions Protruding-mouth hematopoietic multipotent progenitor cell ISH
nr3c1s357/s357 standard conditions Protruding-mouth hematopoietic multipotent progenitor cell ISH
rag2 WT standard conditions Day 5 thymus T cell ISH
nr3c1s357/s357 standard conditions Day 5 thymus T cell ISH
runx1 WT control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT chemical treatment by environment: cortisol Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT chemical treatment by environment: 2-chloro-6-(1-piperazinyl)pyrazine Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT chemical treatment by environment: serotonin Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO1-crhb control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO1-crhb chemical treatment by environment: 2-chloro-6-(1-piperazinyl)pyrazine Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO1-pomca + MO1-pomcb control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO1-pomca + MO1-pomcb chemical treatment by environment: 2-chloro-6-(1-piperazinyl)pyrazine Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO5-nr3c1 control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO5-nr3c1 chemical treatment by environment: cortisol Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
WT + MO5-nr3c1 chemical treatment by environment: serotonin Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
nr3c1s357/s357 control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
nr3c1s357/s357 chemical treatment by environment: serotonin Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment by environment: cortisol Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression increased amount, abnormal
WT chemical treatment by environment: 2-chloro-6-(1-piperazinyl)pyrazine Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression increased amount, abnormal
WT chemical treatment by environment: serotonin Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression increased amount, abnormal
WT + MO1-crhb control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO1-crhb chemical treatment by environment: 2-chloro-6-(1-piperazinyl)pyrazine Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO1-pomca + MO1-pomcb control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO1-pomca + MO1-pomcb chemical treatment by environment: 2-chloro-6-(1-piperazinyl)pyrazine Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO5-nr3c1 control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO5-nr3c1 chemical treatment by environment: cortisol Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
WT + MO5-nr3c1 chemical treatment by environment: serotonin Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
nr3c1s357/s357 control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
nr3c1s357/s357 standard conditions Protruding-mouth hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal
Protruding-mouth hematopoietic multipotent progenitor cell decreased amount, abnormal
Day 5 thymus T cell rag2 expression decreased amount, abnormal
Day 5 thymus T cell decreased amount, abnormal
nr3c1s357/s357 chemical treatment by environment: serotonin Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
pd27Tg; zf169Tg chemical treatment by environment: cortisol Long-pec hematopoietic multipotent progenitor cell increased amount, abnormal
pd27Tg; zf169Tg chemical treatment by environment: 2-chloro-6-(1-piperazinyl)pyrazine Long-pec hematopoietic multipotent progenitor cell increased amount, abnormal
pd27Tg; zf169Tg chemical treatment by environment: serotonin Long-pec hematopoietic multipotent progenitor cell increased amount, abnormal
pd27Tg; zf169Tg + MO1-crhb control Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO1-crhb chemical treatment by environment: 2-chloro-6-(1-piperazinyl)pyrazine Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO1-pomca + MO1-pomcb control Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO1-pomca + MO1-pomcb chemical treatment by environment: 2-chloro-6-(1-piperazinyl)pyrazine Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO5-nr3c1 control Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO5-nr3c1 chemical treatment by environment: cortisol Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
pd27Tg; zf169Tg + MO5-nr3c1 chemical treatment by environment: serotonin Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
Full text @ Cell Stem Cell