FIGURE

Fig. S5

ID
ZDB-FIG-100504-63
Publication
Hartnett et al., 2010 - Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos
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Fig. S5

IGF-2a and IGF-2b regulates the expression of genes involved in dorsal-ventral patterning. (A, B) Expression of chordin is reduced in IGF-2a and IGF-2b morphant embryos. Arrows indicate the width of the chordin expression domain. (C, D) Expression of goosecoid is reduced in IGF-2a and IGF-2b morphant embryos (arrows). (E-J) Expression of bmp2b, bmp4 and gata2 is expanded towards the dorsal side of IGF-2a and IGF-2b morphant embryos (asterisks). Frequency of embryos displaying this staining pattern; A, 13/27; B, 17/35; C, 13/39; D, 17/31; E, 13/27; F, 16/32; G, 12/28; H, 15/36; I, 17/33; J, 21/39. All embryos are shown in a lateral view.

Expression Data
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Shield to 75%-epiboly

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Shield to 75%-epiboly

Phenotype Detail
Acknowledgments
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