ZFIN ID: ZDB-GENE-990415-33
Gene Name: chordin
Gene Symbol: chrd    Nomenclature History

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Previous Names: chd (1), chordino (1), din, dino (din) (1), dino, fe47d04, wu:fe47d04

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Involved in several processes, including embryonic organ development; regionalization; and regulation of BMP signaling pathway. Predicted to localize to the extracellular region. Is expressed in several structures, including anterior neural keel; ectoderm; embryonic structure; median fin; and mesoderm. Orthologous to human CHRD (chordin).
Genome Resources: Alliance (1),  Gene:30161 (1),  Ensembl(GRCz11):ENSDARG00000006110 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b215 Unknown Unknown Unknown G_RAYS
chrd_unspecified Unspecified Unknown Unknown
hi2293Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ko201 Point Mutation Exon 3 Premature Stop CRISPR
    ks1 Unknown Unknown Unknown SPONTANEOUS
    kt440 Unknown Unknown Unknown
    m52 Unknown Unknown Unknown EMS
    rk2 Unknown Unknown Unknown ENU
    tm84 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tt250 Point Mutation Unknown Splice Site, Exon Loss ENU
  • China Zebrafish Resource Center (CZRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-chrd
    1
    CRISPR2-chrd
    1
    CRISPR3-chrd
    1
    CRISPR4-chrd
    1
    CRISPR5-chrd 1
    CRISPR6-chrd
    1
    CRISPR7-chrd
    1
    CRISPR8-chrd
    1
    MO1-chrd N/A 50
    MO2-chrd N/A 1
    TALEN1-chrd
    2
    DISEASE ASSOCIATED WITH chrd HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH chrd VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anterior/posterior axis specification (more)
    Cellular Component extracellular region (more)
    Molecular Function protein binding (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001007 VWFC domain
    Domain IPR010895 CHRD
    Family IPR016353 Chordin
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chrd-202 (1)    Ensembl 3096
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chrd
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hsp70l:chrd) hsp70l chrd Danio rerio 1 6
    MARKER RELATIONSHIPS
    chrd Contained in: [BAC] CH211-229N1 (1)
    chrd Encodes: [EST] fe47d04
    [cDNA] MGC:193864 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_130973 (1) 3178 nt
    Genomic GenBank:CR381579 (1) 130841 nt
    Select Tool
    Polypeptide UniProtKB:B3DH08 (1) 940 aa
    Sequence Information (all 19)
    ORTHOLOGY for chrd ( Chr: 15 )
    CITATIONS (389)