Fig. 3
- ID
- ZDB-FIG-100504-56
- Publication
- Hartnett et al., 2010 - Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos
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IGF-2 regulates the expression of genes involved in dorsal-ventral patterning. (A,C) Embryos injected with control morpholinos show normal chordin and goosecoid expression. (B,D) Expression of chordin and goosecoid is reduced in IGF-2(a+b) morphant embryos (arrows). (E,G,I) Embryos injected with control morpholinos show normal bmp2b, bmp4 and gata2 expression. (F,H,J) Expression of bmp2b, bmp4 and gata2 is expanded towards the dorsal side in IGF-2(a+b) morphant embryos (asterisks). Frequency of embryos displaying this staining pattern; B, 13/26; D, 17/31; F, 16/25; H, 18/32; J, 26/34. All embryos are shown in a lateral view. |
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Stage Range: | Shield to 75%-epiboly |
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Stage Range: | Shield to 75%-epiboly |