Morpholino

MO3-igf2b

ID
ZDB-MRPHLNO-100527-1
Name
MO3-igf2b
Previous Names
None
Target
Sequence
5' - AATGATGTTTTAGTTGGTCCTCCAT - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Translation-blocking MO.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO3-igf2b
Expressed Gene Anatomy Figures
bmp2b Fig. S5 with image from Hartnett et al., 2010
bmp4 Fig. 6 with image,  Fig. S5 with image from Hartnett et al., 2010
chrd Fig. S5 with image from Hartnett et al., 2010
dharma Fig. S3 with image from Hartnett et al., 2010
elnb Fig. 6 with image from Hartnett et al., 2010
fgf8a Fig. S3 with image from Hartnett et al., 2010
gata1a Fig. S6 with image from Hartnett et al., 2010
gata2a Fig. S5 with image from Hartnett et al., 2010
gsc Fig. S5 with image from Hartnett et al., 2010
notch1b Fig. 6 with image from Hartnett et al., 2010
pax6b Fig. S4 with image from Hartnett et al., 2010
rx3 Fig. S4 with image from Hartnett et al., 2010
tal1 Fig. S6 with image from Hartnett et al., 2010
Phenotype
Phenotype resulting from MO3-igf2b
Phenotype Fish Figures
angiogenesis disrupted, abnormal y1Tg + MO3-igf2b text only from Hartnett et al., 2010
apoptotic process increased occurrence, abnormal AB + MO3-igf2b Fig. S4 with image from Hartnett et al., 2010
blood decreased fluid flow, abnormal AB + MO3-igf2b Fig. S6 with image from Hartnett et al., 2010
blood circulation disrupted, abnormal AB + MO3-igf2b Fig. 6 with image,  Fig. S6 with image from Hartnett et al., 2010
brain structure, abnormal AB + MO3-igf2b Fig. 1 with image from Hartnett et al., 2010
bulbus arteriosus morphology, abnormal AB + MO3-igf2b Fig. 6 with image from Hartnett et al., 2010
dorsal/ventral pattern formation disrupted, abnormal AB + MO3-igf2b Fig. S5 with image from Hartnett et al., 2010
eye decreased size, abnormal AB + MO3-igf2b Fig. 1 with image from Hartnett et al., 2010
heart increased size, abnormal AB + MO3-igf2b Fig. 6 with image from Hartnett et al., 2010
heart contraction decreased occurrence, abnormal AB + MO3-igf2b text only from Hartnett et al., 2010
heart looping arrested, abnormal AB + MO3-igf2b Fig. 6 with image from Hartnett et al., 2010
intermediate cell mass of mesoderm distended, abnormal AB + MO3-igf2b Fig. 1 with image from Hartnett et al., 2010
neural keel apoptotic, abnormal AB + MO3-igf2b Fig. S4 with image from Hartnett et al., 2010
post-vent vasculature increased accumulation blood, abnormal AB + MO3-igf2b Fig. S6 with image from Hartnett et al., 2010
somite morphology, abnormal AB + MO3-igf2b Fig. 1 with image from Hartnett et al., 2010
trunk vasculature increased accumulation blood, abnormal AB + MO3-igf2b Fig. S6 with image from Hartnett et al., 2010
vasculature increased accumulation blood, abnormal AB + MO3-igf2b Fig. S6 with image from Hartnett et al., 2010
whole organism decreased length, abnormal AB + MO3-igf2b Fig. 1 with image from Hartnett et al., 2010
whole organism wholly ventralized, abnormal AB + MO3-igf2b Fig. 1 with image,  Fig. S5 with image from Hartnett et al., 2010
Phenotype of all Fish created by or utilizing MO3-igf2b
Phenotype Fish Conditions Figures
post-vent vasculature increased accumulation blood, abnormal AB + MO3-igf2b standard conditions Fig. S6 with image from Hartnett et al., 2010
blood decreased fluid flow, abnormal AB + MO3-igf2b standard conditions Fig. S6 with image from Hartnett et al., 2010
brain structure, abnormal AB + MO3-igf2b standard conditions Fig. 1 with image from Hartnett et al., 2010
whole organism wholly ventralized, abnormal AB + MO3-igf2b standard conditions Fig. 1 with image,  Fig. S5 with image from Hartnett et al., 2010
heart contraction decreased occurrence, abnormal AB + MO3-igf2b standard conditions text only from Hartnett et al., 2010
dorsal/ventral pattern formation disrupted, abnormal AB + MO3-igf2b standard conditions Fig. S5 with image from Hartnett et al., 2010
bulbus arteriosus morphology, abnormal AB + MO3-igf2b standard conditions Fig. 6 with image from Hartnett et al., 2010
trunk vasculature increased accumulation blood, abnormal AB + MO3-igf2b standard conditions Fig. S6 with image from Hartnett et al., 2010
vasculature increased accumulation blood, abnormal AB + MO3-igf2b standard conditions Fig. S6 with image from Hartnett et al., 2010
heart increased size, abnormal AB + MO3-igf2b standard conditions Fig. 6 with image from Hartnett et al., 2010
eye decreased size, abnormal AB + MO3-igf2b standard conditions Fig. 1 with image from Hartnett et al., 2010
somite morphology, abnormal AB + MO3-igf2b standard conditions Fig. 1 with image from Hartnett et al., 2010
blood circulation disrupted, abnormal AB + MO3-igf2b standard conditions Fig. 6 with image,  Fig. S6 with image from Hartnett et al., 2010
apoptotic process increased occurrence, abnormal AB + MO3-igf2b standard conditions Fig. S4 with image from Hartnett et al., 2010
whole organism decreased length, abnormal AB + MO3-igf2b standard conditions Fig. 1 with image from Hartnett et al., 2010
neural keel apoptotic, abnormal AB + MO3-igf2b standard conditions Fig. S4 with image from Hartnett et al., 2010
heart looping arrested, abnormal AB + MO3-igf2b standard conditions Fig. 6 with image from Hartnett et al., 2010
intermediate cell mass of mesoderm distended, abnormal AB + MO3-igf2b standard conditions Fig. 1 with image from Hartnett et al., 2010
angiogenesis disrupted, abnormal y1Tg + MO3-igf2b standard conditions text only from Hartnett et al., 2010
intersegmental vessel sprouting angiogenesis disrupted, abnormal y7Tg + MO2-igf2b + MO3-igf2b + MO4-tp53 standard conditions Fig. 4 with image from Dallinga et al., 2018
intersegmental vessel filopodium decreased amount, abnormal y7Tg + MO2-igf2b + MO3-igf2b + MO4-tp53 standard conditions Fig. 4 with image from Dallinga et al., 2018
blood circulation disrupted, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 4 with image,  Fig. 6 with image from Hartnett et al., 2010
blood decreased fluid flow, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 4 with image from Hartnett et al., 2010
dorsal/ventral pattern formation disrupted, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 3 with image from Hartnett et al., 2010
heart looping arrested, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 6 with image from Hartnett et al., 2010
whole organism decreased length, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 1 with image from Hartnett et al., 2010
brain structure, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 1 with image from Hartnett et al., 2010
vasculature increased accumulation blood, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 4 with image from Hartnett et al., 2010
intermediate cell mass of mesoderm distended, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 1 with image from Hartnett et al., 2010
somite morphology, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 1 with image from Hartnett et al., 2010
post-vent vasculature increased accumulation blood, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 4 with image from Hartnett et al., 2010
apoptotic process increased occurrence, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 2 with image from Hartnett et al., 2010
eye decreased size, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 1 with image from Hartnett et al., 2010
bulbus arteriosus morphology, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 6 with image from Hartnett et al., 2010
trunk vasculature increased accumulation blood, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 4 with image from Hartnett et al., 2010
heart increased size, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 6 with image from Hartnett et al., 2010
heart contraction decreased occurrence, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions text only from Hartnett et al., 2010
whole organism wholly ventralized, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 1 with image,  Fig. 3 with image from Hartnett et al., 2010
neural keel apoptotic, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 2 with image from Hartnett et al., 2010
spinal cord neural keel apoptotic, abnormal AB + MO1-igf2a + MO3-igf2b standard conditions Fig. 2 with image from Hartnett et al., 2010
cranial blood vessel decreased size, abnormal y1Tg + MO1-igf2a + MO3-igf2b standard conditions Fig. 5 with image from Hartnett et al., 2010
angiogenesis disrupted, abnormal y1Tg + MO1-igf2a + MO3-igf2b standard conditions Fig. 5 with image,  Fig. S7 with image,  text only from Hartnett et al., 2010
parachordal vessel hypoplastic, abnormal y1Tg + MO1-igf2a + MO3-igf2b standard conditions Fig. 5 with image from Hartnett et al., 2010
intersegmental vessel decreased size, abnormal y1Tg + MO1-igf2a + MO3-igf2b standard conditions Fig. 5 with image from Hartnett et al., 2010
parachordal vessel morphology, abnormal y1Tg + MO1-igf2a + MO3-igf2b standard conditions Fig. 5 with image from Hartnett et al., 2010
intermediate cell mass of mesoderm distended, abnormal y1Tg + MO1-igf2a + MO3-igf2b standard conditions Fig. 5 with image from Hartnett et al., 2010
intersegmental vessel disorganized, abnormal y1Tg + MO1-igf2a + MO3-igf2b standard conditions Fig. 5 with image from Hartnett et al., 2010
vasculature disorganized, abnormal y1Tg + MO1-igf2a + MO3-igf2b standard conditions Fig. S7 with image from Hartnett et al., 2010
ocular blood vessel decreased size, abnormal y1Tg + MO1-igf2a + MO3-igf2b standard conditions Fig. 5 with image from Hartnett et al., 2010
sprouting angiogenesis decreased occurrence, abnormal y1Tg + MO1-igf2a + MO3-igf2b standard conditions Fig. 5 with image from Hartnett et al., 2010
Citations
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