ZFIN ID: ZDB-FIG-080214-5
Dal-Pra et al., 2006 - Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity. Developmental Biology   298(2):514-526 Full text @ Dev. Biol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-15

Fig. 2 noggin1 morphants display normal D/V patterning. Compared to wild-type at 30 hpf (A), MO-nog1-injected embryos (B) display normal D/V axis, but a thinner yolk tube extension (arrowhead) and a protruding telencephalon. At higher magnification, cerebellum (arrowhead in panel D) appears smaller compared to wild-type (arrowhead in panel C). Lateral views, anterior to the left.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-nog1 standard conditions Prim-15 cerebellum decreased size, abnormal
Prim-15 dorsal/ventral pattern formation process quality, normal
Prim-15 extension decreased thickness, abnormal
Prim-15 midbrain hindbrain boundary decreased thickness, abnormal
Prim-15 telencephalon protruding, abnormal
WT + MO2-nog1 standard conditions Prim-15 cerebellum decreased size, abnormal
Prim-15 dorsal/ventral pattern formation process quality, normal
Prim-15 extension decreased thickness, abnormal
Prim-15 midbrain hindbrain boundary decreased thickness, abnormal
Prim-15 telencephalon protruding, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 298(2), Dal-Pra, S., F├╝rthauer, M., Van-Celst, J., Thisse, B., and Thisse, C., Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity, 514-526, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.