ZFIN Morpholino: MO1-nog1

Target Location

Genome Build: GRCz11Chromosome: 3

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-nog1

No data available

Phenotype

Phenotype resulting from MO1-nog1

Phenotype	Fish	Figures
cerebellum decreased size, abnormal	WT + MO1-nog1	Fig. 2 from Dal-Pra et al., 2006
extension decreased thickness, abnormal	WT + MO1-nog1	Fig. 2 from Dal-Pra et al., 2006
Meckel's cartilage decreased size, abnormal	WT + MO1-nog1	text only from Dal-Pra et al., 2006
midbrain hindbrain boundary decreased thickness, abnormal	WT + MO1-nog1	Fig. 2 from Dal-Pra et al., 2006
pharyngeal arch 3-7 skeleton aplastic, abnormal	WT + MO1-nog1	text only from Dal-Pra et al., 2006

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Phenotype of all Fish created by or utilizing MO1-nog1

Phenotype	Fish	Conditions	Figures
telencephalon protruding, abnormal	WT + MO1-nog1	standard conditions	Fig. 2 from Dal-Pra et al., 2006
extension decreased thickness, abnormal	WT + MO1-nog1	standard conditions	Fig. 2 from Dal-Pra et al., 2006
cerebellum decreased size, abnormal	WT + MO1-nog1	standard conditions	Fig. 2 from Dal-Pra et al., 2006
pharyngeal arch 3-7 skeleton aplastic, abnormal	WT + MO1-nog1	standard conditions	text only from Dal-Pra et al., 2006
Meckel's cartilage decreased size, abnormal	WT + MO1-nog1	standard conditions	text only from Dal-Pra et al., 2006

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Citations

Include unpublished citations

Gao, M., Veil, M., Rosenblatt, M., Riesle, A.J., Gebhard, A., Hass, H., Buryanova, L., Yampolsky, L.Y., Grüning, B., Ulianov, S.V., Timmer, J., Onichtchouk, D. (2022) Pluripotency factors determine gene expression repertoire at zygotic genome activation. Nature communications. 13:788
Tajer, B., Dutko, J.A., Little, S.C., Mullins, M.C. (2021) BMP heterodimers signal via distinct type I receptor class functions. Proceedings of the National Academy of Sciences of the United States of America. 118(15):
Langdon, Y.G., Fuentes, R., Zhang, H., Abrams, E.W., Marlow, F.L., Mullins, M.C. (2016) Split top: A maternal cathepsin B that regulates dorsoventral patterning and morphogenesis. Development (Cambridge, England). 143(6):1016-28
Kapp, L.D., Abrams, E.W., Marlow, F.L., and Mullins, M.C. (2013) The integrator complex subunit 6 (ints6) confines the dorsal organizer in vertebrate embryogenesis. PLoS Genetics. 9(10):e1003822
Zhang, J.L., Patterson, L.J., Qiu, L.Y., Graziussi, D., Sebald, W., and Hammerschmidt, M. (2010) Binding between Crossveinless-2 and Chordin von Willebrand factor type C domains promotes BMP signaling by blocking Chordin activity. PLoS One. 5(9):e12846
Dixon Fox, M., and Bruce, A.E. (2009) Short- and long-range functions of Goosecoid in zebrafish axis formation are independent of Chordin, Noggin 1 and Follistatin-like 1b. Development (Cambridge, England). 136(10):1675-1685
Dal-Pra, S., Fürthauer, M., Van-Celst, J., Thisse, B., and Thisse, C. (2006) Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity. Developmental Biology. 298(2):514-526

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