FIGURE

Fig. 4

ID
ZDB-FIG-061206-9
Publication
Lee et al., 2006 - Canonical Wnt signaling through Lef1 is required for hypothalamic neurogenesis
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Fig. 4

Lef1 is required for proneural and neuronal gene expression in the posterior hypothalamus. White circles outline posterior hypothalamus in whole-mount views, and black ovals outline posterior hypothalamus in cross-sections. Lines in whole-mount images show plane of corresponding cross-sections. (A-D) Expression of sox3 is absent in the posterior hypothalamus of lef1 morphants at 24 hpf. (E-H) Expression of zash1a is absent in the posterior hypothalamus of lef1 morphants at 28 hpf. (I-P) Expression of dlx2 and isl1 are absent in the posterior hypothalamus of lef1 morphants at 30 hpf. (Q-T) Expression of ngn1 and olig2, which are expressed in the posterior tuberculum, is unaffected in the posterior tuberculum of lef1 morphants.

Expression Data
Genes: (all 7)
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Prim-5 to Prim-15

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Prim-5 to Prim-15

Phenotype Detail
Acknowledgments
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